Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Bioactive glasses: from parent 45S5 composition to scaffold-assisted tissue-healing therapies

E Fiume, J Barberi, E Verné, F Baino - Journal of functional biomaterials, 2018 - mdpi.com
Nowadays, bioactive glasses (BGs) are mainly used to improve and support the healing
process of osseous defects deriving from traumatic events, tumor removal, congenital …

Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review

K Deshmukh, T Kovářík, T Křenek, D Docheva, T Stich… - RSC …, 2020 - pubs.rsc.org
The sol–gel derived porous bioactive glasses have drawn worldwide attention by virtue of
the convenience and flexibility of this versatile synthesis method. In this review, the recent …

Bioactive glass-based materials with hierarchical porosity for medical applications: Review of recent advances

F Baino, S Fiorilli, C Vitale-Brovarone - Acta biomaterialia, 2016 - Elsevier
Bioactive glasses have been traditionally used in the clinical practice to fill and restore
osseous defects due to their unique ability to bond to host bone and stimulate new bone …

Bioceramics: from bone regeneration to cancer nanomedicine

M Vallet‐Regí, E Ruiz‐Hernández - Advanced Materials, 2011 - Wiley Online Library
Research on biomaterials has been growing in the last few years due to the clinical needs in
organs and tissues replacement and regeneration. In addition, cancer nanomedicine has …

Controlled dual delivery of BMP-2 and dexamethasone by nanoparticle-embedded electrospun nanofibers for the efficient repair of critical-sized rat calvarial defect

L Li, G Zhou, Y Wang, G Yang, S Ding, S Zhou - Biomaterials, 2015 - Elsevier
There is an urgent need to develop biomimetic bone tissue engineering scaffolds for the
repair of critical-sized calvarial defect. In this study, we developed a new nanoparticle …

Twenty-first century challenges for biomaterials

LL Hench, I Thompson - Journal of the Royal Society …, 2010 - royalsocietypublishing.org
During the 1960s and 1970s, a first generation of materials was specially developed for use
inside the human body. These developments became the basis for the field of biomaterials …

Genetic design of bioactive glass

LL Hench - Journal of the European Ceramic Society, 2009 - Elsevier
This paper reviews the discovery that controlled release of biologically active Ca and Si ions
from bioactive glasses leads to the up-regulation and activation of seven families of genes in …

Bioinspired trimodal macro/micro/nano-porous scaffolds loading rhBMP-2 for complete regeneration of critical size bone defect

W Tang, D Lin, Y Yu, H Niu, H Guo, Y Yuan, C Liu - Acta biomaterialia, 2016 - Elsevier
Critical size bone defects raise great demands for efficient bone substitutes. Mimicking the
hierarchical porous architecture and specific biological cues of natural bone has been …

Bioactive sol‐gel glasses: processing, properties, and applications

F Baino, E Fiume, M Miola… - International Journal of …, 2018 - Wiley Online Library
Sol‐gel route has shown its enormous potential in tissue engineering applications as an
advantageous method for the production of bioactive glasses aimed at regenerating both …