Matrix assisted laser desorption time of flight mass spectrometry (MALDI-TOF MS) in clinical microbiology

S Angeletti - Journal of microbiological methods, 2017 - Elsevier
The microbiological management of patients with suspected bacterial infection includes the
identification of the pathogen and the determination of the antibiotic susceptibility. These …

MALDI-TOF mass spectrometry for microorganism identification

TC Dingle, SM Butler-Wu - Clinics in laboratory medicine, 2013 - labmed.theclinics.com
The clinical microbiology laboratory plays a critical role in patient care by providing definitive
knowledge of the cause of infection and antimicrobial susceptibility data to physicians …

Current Taxonomical Situation of Streptococcus suis

M Okura, M Osaki, R Nomoto, S Arai, R Osawa… - Pathogens, 2016 - mdpi.com
Streptococcus suis, a major porcine pathogen and an important zoonotic agent, is
considered to be composed of phenotypically and genetically diverse strains. However …

Novel approach for differentiating Shigella species and Escherichia coli by matrix-assisted laser desorption ionization–time of flight mass spectrometry

PD Khot, MA Fisher - Journal of clinical microbiology, 2013 - Am Soc Microbiol
Shigella species are so closely related to Escherichia coli that routine matrix-assisted laser
desorption/ionization–time of flight mass spectrometry (MALDI-TOF MS) cannot reliably …

Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based …

BW Buchan, CC Ginocchio, R Manii… - PLOS …, 2013 - journals.plos.org
Background A multicenter study was conducted to evaluate the diagnostic accuracy
(sensitivity and specificity) of the Verigene Gram-Positive Blood Culture Test (BC-GP) test to …

Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020

DA Tavares, S Handem, RJ Carvalho, AC Paulo… - Scientific reports, 2019 - nature.com
Real-time PCR targeting lytA (the major autolysin gene) and piaB (permease gene of the pia
ABC transporter) are currently used as the gold-standard culture-independent assays for …

Current challenges in the accurate identification of Streptococcus pneumoniae and its serogroups/serotypes in the vaccine era

R Varghese, R Jayaraman, B Veeraraghavan - Journal of microbiological …, 2017 - Elsevier
Streptococcus pneumoniae is a major cause of pneumonia, meningitis and other invasive
diseases resulting in high mortality and morbidity among children under the age of five …

Identification of Streptococcus pneumoniae and other Mitis streptococci: importance of molecular methods

E Sadowy, W Hryniewicz - European Journal of Clinical Microbiology & …, 2020 - Springer
The Mitis group of streptococci includes an important human pathogen, Streptococcus
pneumoniae (pneumococcus) and about 20 other related species with much lower …

Accurate Differentiation of Streptococcus pneumoniae from other Species within the Streptococcus mitis Group by Peak Analysis Using MALDI-TOF MS

M Marín, E Cercenado, C Sánchez-Carrillo… - Frontiers in …, 2017 - frontiersin.org
Despite the benefits of MALDI-TOF MS technology (Matrix-Assisted Laser Desorption-
Ionization Time-Of-Flight Mass Spectrometry) reported worldwide and the continuous …

Discrimination of major and minor streptococci incriminated in bovine mastitis by MALDI-TOF MS fingerprinting and 16S rRNA gene sequencing

MEA Alnakip, NR Rhouma, EN Abd-Elfatah… - Research in Veterinary …, 2020 - Elsevier
The current work investigated the discriminatory potential of MALDI-TOF MS fingerprinting
towards most-relevant major (Streptococcus agalactiae, S. dysgalactiae, S. uberis) and …