For decades, immunologists have studied the role of circulating immune cells in host
protection, with a more recent appreciation of immune cells resident within the tissue …

The immune system plays a pivotal role in the initiation, development and resolution of
inflammation following insult or damage to organs. The heart is a vital organ which supplies …

Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …

Type 2 immunity mediates protective responses to helminths and pathological responses to
allergens, but it also has broad roles in the maintenance of tissue integrity, including wound …

Many chronic diseases are marked by fibrosis, which is defined by an abundance of
activated fibroblasts and excessive deposition of extracellular matrix, resulting in loss of …

Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

Inflammation must be tightly regulated to both defend against pathogens and restore tissue
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …

Mammalian models including non‐human primates, pigs and rodents have been used
extensively to study the mechanisms of cardiovascular disease. However, there is an …

The stromal‐derived factor 1α/chemokine receptor 4 (SDF‐1α/CXCR4) axis contributes to
myocardial protection after myocardial infarction (MI) by recruiting endogenous stem cells …

Objective: This study aimed to explore the role of circular RNAs (circRNAs) in M2
macrophage (M2M)-derived small extracellular vesicles (SEVs) in myocardial fibrosis …