Antiphospholipid Syndrome Antiphospholipid antibodies can induce endothelial-cell,
complement, platelet, neutrophil, and monocyte activation, leading to thrombosis, renal …

Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Objectives To assess the prevalence of the main causes of morbi-mortality in the
antiphospholipid syndrome (APS) during a 10-year-follow-up period and to compare the …

Background High-quality anticoagulation management is required to keep these narrow
therapeutic index medications as effective and safe as possible. This article focuses on the …

Objectives To develop recommendations for the diagnosis, prevention and treatment of
neuropsychiatric systemic lupus erythematosus (NPSLE) manifestations. Methods The …

Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable
presentations, course and prognosis. We sought to develop evidence-based …

Background Many patients with the antiphospholipid antibody syndrome and recurrent
thrombosis receive doses of warfarin adjusted to achieve an international normalized ratio …

Background: The optimal intensity of oral anticoagulation for the prevention of recurrent
thrombosis in patients with antiphospholipid antibody syndrome is uncertain. Retrospective …

ContextThe presence of antiphospholipid antibodies (aPL) has been associated with
vascular occlusive events. However, the role of aPL in predicting ischemic events …

Objectives: To identify the main causes of morbidity and mortality in patients with
antiphospholipid syndrome (APS) during a 5-year period and to determine clinical and …