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Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering
Regenerative engineering converges tissue engineering, advanced materials science, stem
cell science, and developmental biology to regenerate complex tissues such as whole limbs …
cell science, and developmental biology to regenerate complex tissues such as whole limbs …
[HTML][HTML] Models of osteoarthritis: the good, the bad and the promising
Osteoarthritis (OA) is a chronic degenerative disease of diarthrodial joints most commonly
affecting people over the age of forty. The causes of OA are still unknown and there is much …
affecting people over the age of forty. The causes of OA are still unknown and there is much …
Bioceramic composites for orthopaedic applications: A comprehensive review of mechanical, biological, and microstructural properties
Bioceramics have been widely utilized for orthopaedic applications in which the
biocompatibility and mechanical properties of the materials are vital characteristics to be …
biocompatibility and mechanical properties of the materials are vital characteristics to be …
Cartilage tissue engineering: molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction
M Demoor, D Ollitrault, T Gomez-Leduc… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Articular cartilage defects are a veritable therapeutic problem because
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …
Functional attachment of soft tissues to bone: development, healing, and tissue engineering
Connective tissues such as tendons or ligaments attach to bone across a multitissue
interface with spatial gradients in composition, structure, and mechanical properties. These …
interface with spatial gradients in composition, structure, and mechanical properties. These …
Engineering complex tissues
This article summarizes the views expressed at the third session of the workshop" Tissue
Engineering—The Next Generation," which was devoted to the engineering of complex …
Engineering—The Next Generation," which was devoted to the engineering of complex …
In situ measurement of transport between subchondral bone and articular cartilage
Subchondral bone and articular cartilage play complementary roles in load bearing of the
joints. Although the biomechanical coupling between subchondral bone and articular …
joints. Although the biomechanical coupling between subchondral bone and articular …
Scaffold fiber diameter regulates human tendon fibroblast growth and differentiation
The diameter of collagen fibrils in connective tissues, such as tendons and ligaments is
known to decrease upon injury or with age, leading to inferior biomechanical properties and …
known to decrease upon injury or with age, leading to inferior biomechanical properties and …
In vivo evaluation of a multiphased scaffold designed for orthopaedic interface tissue engineering and soft tissue‐to‐bone integration
Achieving functional graft integration with subchondral bone poses a significant challenge
for orthopaedic soft tissue repair and reconstruction. Soft tissues such as the anterior …
for orthopaedic soft tissue repair and reconstruction. Soft tissues such as the anterior …
Development of controlled matrix heterogeneity on a triphasic scaffold for orthopedic interface tissue engineering
Biological fixation of orthopedic soft tissue grafts to bone poses a significant clinical
challenge. The clinical success of soft tissue–based grafts for anterior cruciate ligament …
challenge. The clinical success of soft tissue–based grafts for anterior cruciate ligament …