Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Drug delivery to the central nervous system
Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug
development remains challenging, with high costs, long pathways to clinical use and high …
development remains challenging, with high costs, long pathways to clinical use and high …
The PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities
X He, Y Li, B Deng, A Lin, G Zhang, M Ma… - Cell …, 2022 - Wiley Online Library
Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below
the injured segment of the spinal cord, which significantly impacts the quality of life in …
the injured segment of the spinal cord, which significantly impacts the quality of life in …
Acute traumatic spinal cord injury
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …
Traumatic spinal cord injury
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …
vocational well-being of patients. The demographic of SCIs is shifting such that an …
Modern medical management of spinal cord injury
Abstract Purpose of Review Spinal cord injury (SCI) shows an incidence of 10.4–83
cases/million/year globally and remains a significant source of morbidity and cost to society …
cases/million/year globally and remains a significant source of morbidity and cost to society …
Immune response following traumatic spinal cord injury: Pathophysiology and therapies
RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
Trauma: spinal cord injury
Traumatic spine and spinal cord injury (SCI) occurred in roughly 17,000 US citizens in 2016,
with an estimated prevalence of approximately 280,000 injured persons. 1 Although the …
with an estimated prevalence of approximately 280,000 injured persons. 1 Although the …
Assessment and management of acute spinal cord injury: From point of injury to rehabilitation
LD Hachem, CS Ahuja, MG Fehlings - The journal of spinal cord …, 2017 - Taylor & Francis
Context: Spinal cord injury (SCI) is a devastating condition that can lead to significant
neurological impairment and reduced quality of life. Despite advancements in our …
neurological impairment and reduced quality of life. Despite advancements in our …
A clinical practice guideline for the management of acute spinal cord injury: introduction, rationale, and scope
MG Fehlings, LA Tetreault, JR Wilson… - Global spine …, 2017 - journals.sagepub.com
Acute spinal cord injury (SCI) is a traumatic event that results in disturbances to normal
sensory, motor, or autonomic function and ultimately affects a patient's physical …
sensory, motor, or autonomic function and ultimately affects a patient's physical …