[HTML][HTML] Engineered tumor cell-derived vaccines against cancer: The art of combating poison with poison

X Zhang, H Cui, W Zhang, Z Li, J Gao - Bioactive Materials, 2023 - Elsevier
Tumor vaccination is a promising approach for tumor immunotherapy because it presents
high specificity and few side effects. However, tumor vaccines that contain only a single …

Research progress of microneedles in the treatment of melanoma

X Li, Z Zhao, M Zhang, G Ling, P Zhang - Journal of controlled release, 2022 - Elsevier
Melanoma is an aggressive malignancy deriving from melanocytes, which is characterized
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …

Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of …

K Peng, LK Vora, IA Tekko, AD Permana… - Journal of Controlled …, 2021 - Elsevier
Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …

Hydrogel-forming microneedles for rapid and efficient skin deposition of controlled release tip-implants

K Peng, LK Vora, J Domínguez-Robles… - Materials Science and …, 2021 - Elsevier
In this work, we introduce, for the first time, novel hybrid microneedle patches with
implantable poly (lactic-co-glycolic acid)(PLGA) tips aligned with hydrogel-forming …

Trilayer microneedle array assisted transdermal and intradermal delivery of dexamethasone

M Li, LK Vora, K Peng, RF Donnelly - International Journal of …, 2022 - Elsevier
Dexamethasone is a synthesised glucocorticoid that is widely used in the treatment of
various inflammatory skin conditions. Novel trilayer dissolving microneedle arrays were …

Nanomaterial-based drug delivery systems as promising carriers for patients with COVID-19

M Abd Elkodous, SO Olojede, M Morsi, GS El-Sayyad - RSC advances, 2021 - pubs.rsc.org
Once the World Health Organization (WHO) declared the COVID-19 outbreak to be
pandemic, massive efforts have been launched by researchers around the globe to combat …

Advances in cancer vaccine research

N Liu, X **ao, Z Zhang, C Mao, M Wan… - … Biomaterials Science & …, 2023 - ACS Publications
The use of cancer vaccines is considered a promising therapeutic strategy in clinical
oncology, which is achieved by stimulating antitumor immunity with tumor antigens delivered …

Probing the Biosafety of Implantable Artificial Secretory Granules for the Sustained Release of Bioactive Proteins

P Álamo, E Parladé, MTP Favaro… - … applied materials & …, 2023 - ACS Publications
Among bio-inspired protein materials, secretory protein microparticles are of clinical interest
as self-contained, slow protein delivery platforms that mimic secretory granules of the human …

Long-term vaccine delivery and immunological responses using biodegradable polymer-based carriers

A Malek-Khatabi, Z Tabandeh, A Nouri… - ACS Applied Bio …, 2022 - ACS Publications
Biodegradable polymers are largely employed in the biomedical field, ranging from tissue
regeneration to drug/vaccine delivery. The biodegradable polymers are highly …

Recent advances of polymeric nanoplatforms for cancer treatment: smart delivery systems (SDS), nanotheranostics and multidrug resistance (MDR) inhibition

U Gupta, D Maity, VK Sharma - Biomedical Materials, 2023 - iopscience.iop.org
Nanotheranostics is a promising field that combines the benefits of diagnostic and treatment
into a single nano-platform that not only administers treatment but also allows for real-time …