Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

INTRODUCTION The ability to regenerate tissues lost to damage or disease is widely but
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate …

Abstract Model organisms are widely used in research as accessible and convenient
systems to study a particular area or question in biology. Traditionally only a handful of …

The zebrafish has emerged as a powerful vertebrate model for studying liver‐associated
disorders. Liver damage is a crucial problem in the process of drug development and …

Turquoise killifish (Nothobranchius furzeri) are naturally short-lived vertebrates that display a
wide range of spontaneous age-related changes, including onset of cancer, reduced …

Late-life-initiated dietary interventions show limited efficacy in extending longevity or
mitigating frailty, yet the underlying causes remain unclear. Here we studied the age-related …

Worldwide, people are getting older, and this prolonged lifespan unfortunately also results in
an increased prevalence of age-related neurodegenerative diseases, contributing to a …

The young African turquoise killifish has a high regenerative capacity, but loses it with
advancing age, adopting several aspects of the limited form of mammalian regeneration. We …

The turquoise killifish, Nothobranchius furzeri, is a promising vertebrate model in ageing
research and an emerging model organism in genomics, regenerative medicine …