Translational considerations in injectable cell-based therapeutics for neurological applications: concepts, progress and challenges

MH Amer, FRAJ Rose, KM Shakesheff… - NPJ Regenerative …, 2017 - nature.com
Significant progress has been made during the past decade towards the clinical adoption of
cell-based therapeutics. However, existing cell-delivery approaches have shown limited …

Muscle injury and repair

Y Li, J Cummins, J Huard - Current opinion in orthopaedics, 2001 - journals.lww.com
Muscle injury presents a challenging problem in traumatology and is frequently encountered
in sports medicine. The injury can occur via a variety of mechanisms, ranging from direct …

[HTML][HTML] High glucose inhibits myogenesis and induces insulin resistance by down-regulating AKT signaling

W Luo, L Ai, B Wang, Y Zhou - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Background A high glucose level is usually considered to be the factor that induces tissue
and cell dysfunction and damage, commonly known as “glucose toxicity”. Objective This …

Use of a novel collagen matrix with oriented pore structure for muscle cell differentiation in cell culture and in grafts

V Kroehne, I Heschel, F Schügner… - Journal of cellular …, 2008 - Wiley Online Library
Tissue engineering of skeletal muscle from cultured cells has been attempted using a variety
of synthetic and natural macromolecular scaffolds. Our study describes the application of …

Dynamics and mediators of acute graft attrition after myoblast transplantation to the heart

K Suzuki, B Murtuza, JR Beauchamp… - The FASEB …, 2004 - Wiley Online Library
Survival and proliferation of skeletal myoblasts within the cardiac environment are crucial to
the therapeutic efficacy of myoblast transplantation to the heart. We have analyzed the early …

Antifibrotic effects of suramin in injured skeletal muscle after laceration

YS Chan, Y Li, W Foster, T Horaguchi… - Journal of applied …, 2003 - journals.physiology.org
Muscle injuries are very common in traumatology and sports medicine. Although muscle
tissue can regenerate postinjury, the healing process is slow and often incomplete; complete …

Craniofacial muscle engineering using a 3-dimensional phosphate glass fibre construct

R Shah, ACM Sinanan, JC Knowles, NP Hunt… - Biomaterials, 2005 - Elsevier
The current technique to replace missing craniofacial skeletal muscle is the surgical transfer
of local or free flaps. This is associated with donor site morbidity, possible tissue rejection …

Periurethral injection of autologous adipose-derived stem cells with controlled-release nerve growth factor for the treatment of stress urinary incontinence in a rat …

W Zhao, C Zhang, C **, Z Zhang, D Kong, W Xu, Y **u - European urology, 2011 - Elsevier
BACKGROUND: Stem cell therapy is a promising therapeutic strategy for stress urinary
incontinence (SUI). However, its current efficacy is insufficient. OBJECTIVE: We designed a …

Matrigel, but not collagen I, maintains the differentiation capacity of muscle derived cells in vitro

S Grefte, S Vullinghs, AM Kuijpers-Jagtman… - Biomedical …, 2012 - iopscience.iop.org
Satellite cells are key cells for post-natal muscle growth and regeneration and they play a
central role in the search for therapies to treat muscle injuries. In this study the proliferation …

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

MN González, W de Mello, GS Butler-Browne… - Skeletal Muscle, 2017 - Springer
Background The hepatocyte growth factor (HGF) is required for the activation of muscle
progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC …