[HTML][HTML] Mechanism of metabolic dysfunction-associated steatotic liver disease: important role of lipid metabolism

X Feng, R Zhang, Z Yang, K Zhang… - Journal of Clinical and …, 2024 - pmc.ncbi.nlm.nih.gov
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-
alcoholic fatty liver disease, has a high global prevalence and can progress to metabolic …

Rodent model of metabolic dysfunction‐associated fatty liver disease: a systematic review

XS Cui, HZ Li, L Li, CZ ** preclinical models for metabolic
dysfunction‐associated steatotic liver disease (MASLD), few have encapsulated the …

NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA

Z Wang, X Wan, MA Khan, L Peng, X Sun, X Yi… - Lipids in Health and …, 2024 - Springer
Background Metabolic dysfunction associated steatotic liver disease (MASLD), closely
linked to excessive lipogenesis, induces chronic liver disease. MASLD often cause other …

[HTML][HTML] Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis

K Buyl, M Vrints, R Fernando, T Desmae… - European Journal of …, 2023 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-
alcoholic fatty liver disease (NAFLD), is characterized by intrahepatic triglyceride …

Macrophage SREBP1 regulates skeletal muscle regeneration

Y Oishi, H Koike, N Kumagami, Y Nakagawa… - Frontiers in …, 2024 - frontiersin.org
Macrophages are essential for the proper inflammatory and reparative processes that lead
to regeneration of skeletal muscle after injury. Recent studies have demonstrated close links …

[HTML][HTML] Zhuyu pill attenuates metabolic-associated fatty liver disease by regulating macrophage polarization through TLR4 signaling pathway

M Zhao, Q He, X Shu, R Xu, Z Zhang, Y Mou, W Liao… - Phytomedicine, 2025 - Elsevier
Background Metabolic-associated fatty liver disease (MAFLD) is the leading chronic liver
disease globally, impacting a large segment of the population. The Zhuyu Pill (ZYP), a …

Citrullus mucosospermus Extract Exerts Protective Effects against Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis in Mice

SY Park, JE Kim, HM Kang, KH Park, BI Je, KW Lee… - Foods, 2024 - mdpi.com
In recent years, there has been increasing interest in exploring the potential therapeutic
advantages of Citrullus mucosospermus extracts (CME) for nonalcoholic steatohepatitis …

[HTML][HTML] Molecular mechanisms of metabolic disease-associated hepatic inflammation in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

C Zhang, Y Sui, S Liu, M Yang - Exploration of Digestive …, 2023 - explorationpub.com
Non-alcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide,
with a progressive form of non-alcoholic steatohepatitis (NASH). It may progress to …

[PDF][PDF] The role of cholesterol metabolism and its regulation in tumor development

W Song, J He, X Wu, M Su, R Hu… - World J. Surg. Surg …, 2024 - surgeryresearchjournal.com
Cholesterol and its metabolites play a crucial role in cancer development and suppression
of immune responses. In recent years, a large number of experimental and clinical studies …

Mechanism of action of sterol regulatory element-binding proteins in nonalcoholic fatty liver disease and related therapeutic targets

LI Anqi, Y **g - 临床肝胆病杂志, 2024 - lcgdbzz.com
Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disease in the
world and is an important risk factor for the progression to hepatocellular carcinoma …