Function and genetics of dystrophin and dystrophin-related proteins in muscle
DJ Blake, A Weir, SE Newey… - Physiological …, 2002 - journals.physiology.org
The X-linked muscle-wasting disease Duchenne muscular dystrophy is caused by mutations
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …
Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues
V Bennett, AJ Baines - Physiological reviews, 2001 - journals.physiology.org
The spectrin-based membrane skeleton of the humble mammalian erythrocyte has provided
biologists with a set of interacting proteins with diverse roles in organization and survival of …
biologists with a set of interacting proteins with diverse roles in organization and survival of …
PDZ domains and the organization of supramolecular complexes
▪ Abstract PDZ domains are modular protein interaction domains that bind in a sequence-
specific fashion to short C-terminal peptides or internal peptides that fold in a β-finger. The …
specific fashion to short C-terminal peptides or internal peptides that fold in a β-finger. The …
Mechanism and role of PDZ domains in signaling complex assembly
BZ Harris, WA Lim - Journal of cell science, 2001 - journals.biologists.com
PDZ domains are protein-protein recognition modules that play a central role in organizing
diverse cell signaling assemblies. These domains specifically recognize short C-terminal …
diverse cell signaling assemblies. These domains specifically recognize short C-terminal …
PDZ domains: structural modules for protein complex assembly
AY Hung, M Sheng - Journal of Biological Chemistry, 2002 - ASBMB
PDZ domains1 are modular protein interaction domains that play a role in protein targeting
and protein complex assembly. Once termed Discs-large homology regions (DHRs) or …
and protein complex assembly. Once termed Discs-large homology regions (DHRs) or …
AnkyrinG Is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing
D Zhou, S Lambert, PL Malen, S Carpenter… - The Journal of cell …, 1998 - rupress.org
Voltage-gated sodium channels (NaCh) are colocalized with isoforms of the membrane-
skeletal protein ankyrinG at axon initial segments, nodes of Ranvier, and postsynaptic folds …
skeletal protein ankyrinG at axon initial segments, nodes of Ranvier, and postsynaptic folds …
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
The clustered, regularly interspaced, short palindromic repeats (CRISPR)-associated protein
Cas9 from Streptococcus pyogenes is an RNA-guided DNA endonuclease with widespread …
Cas9 from Streptococcus pyogenes is an RNA-guided DNA endonuclease with widespread …
PSD-95 Assembles a Ternary Complex with theN-Methyl-D-aspartic Acid Receptor and a Bivalent Neuronal NO Synthase PDZ Domain
Nitric oxide (NO) biosynthesis in cerebellum is preferentially activated by calcium influx
throughN-methyl-d-aspartate (NMDA)-type glutamate receptors, suggesting that there is a …
throughN-methyl-d-aspartate (NMDA)-type glutamate receptors, suggesting that there is a …
Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex
The PDZ protein interaction domain of neuronal nitric oxide synthase (nNOS) can
heterodimerize with the PDZ domains of postsynaptic density protein 95 and syntrophin …
heterodimerize with the PDZ domains of postsynaptic density protein 95 and syntrophin …
The dystrophin–glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies
TA Rando - Muscle & nerve, 2001 - Wiley Online Library
Mutations of different components of the dystrophin–glycoprotein complex (DGC) cause
muscular dystrophies that vary in terms of severity, age of onset, and selective involvement …
muscular dystrophies that vary in terms of severity, age of onset, and selective involvement …