BRAF mutations in melanoma: biological aspects, therapeutic implications, and circulating biomarkers
G Castellani, M Buccarelli, MB Arasi, S Rossi… - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous melanoma represents the most aggressive form of skin cancer
and its occurrence, development, and progression are based on the accumulation of several …
and its occurrence, development, and progression are based on the accumulation of several …
Dihydrolipoamide dehydrogenase (DLD) is a novel molecular target of bortezomib
Y Feng, H Luo, J Huang, Y Zhang, J Wen, L Li… - Cell Death & …, 2024 - nature.com
Proteasome inhibitors (PIs), such as bortezomib and calfizomib, were backbone agents in
the treatment of multiple myeloma (MM). In this study, we investigated bortezomib interactors …
the treatment of multiple myeloma (MM). In this study, we investigated bortezomib interactors …
[PDF][PDF] Mendelian randomization study reveals a predicted relationship between sensorineural hearing loss and mitochondrial proteins
J Yan, L Wu, M Zheng, Y Lv, F Jiang, W Gao… - Otology & …, 2024 - journals.lww.com
Background Mitochondrial proteins assume a pivotal role in the onset and progression of
diverse diseases. Nonetheless, the causal interconnections with sensorineural hearing loss …
diverse diseases. Nonetheless, the causal interconnections with sensorineural hearing loss …
The prognostic implications of cuproptosis‐related gene signature and the potential of PPIC as a promising biomarker in cutaneous melanoma
B Zhou, S Sha, Q Wang, S Sun, J Tao… - Pigment Cell & …, 2024 - Wiley Online Library
Cutaneous melanoma is the most lethal of all skin tumors. Recently, cuproptosis, a novel
form of cell death linked to oxidative phosphorylation, has emerged as an important factor …
form of cell death linked to oxidative phosphorylation, has emerged as an important factor …
DLD is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients
C Chen, D Kang, Z Chen, P Shi, Y Li, S Qian - Apoptosis, 2024 - Springer
Since the discovery of copper induces cell death (cuprotosis) in 2022, it has been one of the
biggest research hotspots. cuprotosis related genes (CRGs) has been demonstrated to be a …
biggest research hotspots. cuprotosis related genes (CRGs) has been demonstrated to be a …
Alpha-2-Macroglobulin Is a Novel Anticancer Agent
Introduction: Melanoma is the most aggressive skin cancer, with an increasing occurrence.
Despite the recent important improvements due to novel immunotherapy approaches, when …
Despite the recent important improvements due to novel immunotherapy approaches, when …
Novel cuproptosis-related prognostic gene profiles in preeclampsia
X Tang, Y Liu, Y Zhang - BMC Pregnancy and Childbirth, 2024 - Springer
Background Preeclampsia (PE) is a pregnancy-specific disorder with complex
pathogenesis. Cuproptosis is a novel identified form of programmed cell death, however, the …
pathogenesis. Cuproptosis is a novel identified form of programmed cell death, however, the …
Identification of a cuproptosis-associated gene signature and Peptidylprolyl isomerase C as therapeutic target in cutaneous melanoma
B Zhou, S Sha, L Yang, Y Fu, L Tan, S Sun, J Li… - 2023 - researchsquare.com
Cutaneous melanoma is widely known to be the most lethal of skin tumors. Cuproptosis is a
newly discovered cell death form which is related to the process of oxidative …
newly discovered cell death form which is related to the process of oxidative …
Alpha-2-Macroglobulin Is a Novel Anticancer Agent
FFD DLArcangelob, A Facchianob - 2023 - karger.com
Introduction: Melanoma is the most aggressive skin cancer, with an increasing occurrence.
Despite the recent important improvements due to novel immunotherapy approaches, when …
Despite the recent important improvements due to novel immunotherapy approaches, when …