Nociplastic pain is a mechanistic term used to describe pain that arises or is sustained by
altered nociception, despite the absence of tissue damage. Although nociplastic pain has …

Interstitial cystitis/bladder pain syndrome is a debilitating condition of unknown etiology
characterized by persistent pelvic pain with lower urinary tract symptoms and comprises a …

Psychiatric sequelae substantially contribute to the post-acute burden of disease associated
with COVID-19, persisting months after clearance of the virus. Brain imaging shows white …

Centralized pain syndromes are associated with changes within the central nervous system
that amplify peripheral input and/or generate the perception of pain in the absence of a …

Purpose: To provide a clinical framework for the diagnosis and treatment of interstitial
cystitis/bladder pain syndrome. Materials and Methods: A systematic review of the literature …

The development of chronic pain is a complex mechanism that is still not fully understood.
Multiple somatic and visceral afferent pain signals, when experienced over time, cause a …

Central sensitization refers to the amplification of pain by central nervous system
mechanisms. Classically described as a consequence of ongoing nociceptive input, it is …

Urologic chronic pelvic pain syndrome (UCPPS), which encompasses interstitial
cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome, is …

Definitive diagnosis and selection of effective treatment for chronic prostatitis/chronic pelvic
pain syndrome (CP/CPPS) are frustrations encountered frequently by urology care providers …

Interstitial cystitis/bladder pain syndrome is a chronic pain syndrome whose causes remains
elusive with no generally accepted treatment. A hallmark of functional pain syndromes such …