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Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
The gut microbiome in Alzheimer's disease: what we know and what remains to be explored
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …
sustained decline in cognition. There are currently few effective disease modifying therapies …
Gut microbiome composition may be an indicator of preclinical Alzheimer's disease
Alzheimer's disease (AD) pathology is thought to progress from normal cognition through
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …
[HTML][HTML] The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …
[HTML][HTML] Microbiota-derived metabolite Indoles induced aryl hydrocarbon receptor activation and inhibited neuroinflammation in APP/PS1 mice
J Sun, Y Zhang, Y Kong, T Ye, Q Yu… - Brain, Behavior, and …, 2022 - Elsevier
Gut microbiota alterations might affect the development of Alzheimer's disease (AD) through
microbiota-derived metabolites. For example, microbiota-derived Indoles via tryptophan …
microbiota-derived metabolites. For example, microbiota-derived Indoles via tryptophan …
Short-chain fatty acids and human health: from metabolic pathways to current therapeutic implications
S Facchin, L Bertin, E Bonazzi, G Lorenzon… - Life, 2024 - mdpi.com
The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as
the gut microbiota, which play a pivotal role in breaking down undigested foods, such as …
the gut microbiota, which play a pivotal role in breaking down undigested foods, such as …
Gut microbiome-targeted therapies for Alzheimer's disease
T Zhang, G Gao, LY Kwok, Z Sun - Gut Microbes, 2023 - Taylor & Francis
The advent of highthroughput 'omics' technologies has improved our knowledge of gut
microbiome in human health and disease, including Alzheimer's disease (AD), a …
microbiome in human health and disease, including Alzheimer's disease (AD), a …
Association of dietary live microbes and nondietary prebiotic/probiotic intake with cognitive function in older adults: evidence from NHANES
Background The current study aims to examine association of dietary live microbes and
nondietary prebiotic/probiotic intake with cognitive function among older US adults …
nondietary prebiotic/probiotic intake with cognitive function among older US adults …
Correlation between the gut microbiome and neurodegenerative diseases: a review of metagenomics evidence
X Liu, Y Liu, J Liu, H Zhang, C Shan… - Neural Regeneration …, 2024 - journals.lww.com
A growing body of evidence suggests that the gut microbiota contributes to the development
of neurodegenerative diseases via the microbiota-gut-brain axis. As a contributing factor …
of neurodegenerative diseases via the microbiota-gut-brain axis. As a contributing factor …
Gut microbiota-host lipid crosstalk in Alzheimer's disease: implications for disease progression and therapeutics
YX Luo, LL Yang, XQ Yao - Molecular Neurodegeneration, 2024 - Springer
Trillions of intestinal bacteria in the human body undergo dynamic transformations in
response to physiological and pathological changes. Alterations in their composition and …
response to physiological and pathological changes. Alterations in their composition and …