MicroRNAs and complex diseases: from experimental results to computational models
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …
viruses and animals. As one of the most important components in the cell, miRNAs play a …
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
Early studies have shown how aberrantly expressed microRNAs are a hallmark of several
diseases like cancer. MicroRNA expression profiling was shown to be associated with …
diseases like cancer. MicroRNA expression profiling was shown to be associated with …
Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …
methods and in rational drug design, the increase in approved drugs in the past decade did …
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions
MicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively
regulating gene expression to control many cellular mechanisms. The miRTarBase …
regulating gene expression to control many cellular mechanisms. The miRTarBase …
miRTarBase: a database curates experimentally validated microRNA–target interactions
MicroRNAs (miRNAs), ie small non-coding RNA molecules (∼ 22 nt), can bind to one or
more target sites on a gene transcript to negatively regulate protein expression …
more target sites on a gene transcript to negatively regulate protein expression …
Genome-wide survey of tissue-specific microRNA and transcription factor regulatory networks in 12 tissues
Z Guo, M Maki, R Ding, Y Yang, B Zhang, L **ong - Scientific reports, 2014 - nature.com
Tissue-specific miRNAs (TS miRNA) specifically expressed in particular tissues play an
important role in tissue identity, differentiation and function. However, transcription factor …
important role in tissue identity, differentiation and function. However, transcription factor …
Important aspects of Toll-like receptors, ligands and their signaling pathways
ZL Chang - Inflammation research, 2010 - Springer
Due to the rapid increase of new information on the multiple roles of Toll-like receptors
(TLRs), this paper reviews several main properties of TLRs and their ligands and signaling …
(TLRs), this paper reviews several main properties of TLRs and their ligands and signaling …
Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes
Background Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the
articular cartilage due to environmental, mechanical and genetic components. The genetics …
articular cartilage due to environmental, mechanical and genetic components. The genetics …
Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis
K Skrzypek, M Tertil, S Golda, M Ciesla… - Antioxidants & redox …, 2013 - liebertpub.com
Abstract Aims: Heme oxygenase-1 (HO-1, HMOX1) can prevent tumor initiation; while in
various tumors, it has been demonstrated to promote growth, angiogenesis, and metastasis …
various tumors, it has been demonstrated to promote growth, angiogenesis, and metastasis …