The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

We present the science and technology roadmap for graphene, related two-dimensional
crystals, and hybrid systems, targeting an evolution in technology, that might lead to impacts …

Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …

Graphene as a star in materials research has been attracting tremendous attentions in the
past few years in various fields including biomedicine. In this work, for the first time we …

To date, various nanomaterials with the ability for gene delivery or photothermal effect have
been developed in the field of biomedicine. The therapeutic potential of these nanomaterials …

In many ways, cancer cells are different from healthy cells. A lot of tactical nano-based drug
delivery systems are based on the difference between cancer and healthy cells. Currently …

The current medical reality of cancer gene therapy is reflected by more than ten approved
products on the global market, including oncolytic and other viral vectors and CAR T-cells as …

In order to elicit therapeutic effects, many drugs including small molecule anticancer drugs,
proteins, siRNA, and DNA have to be delivered and released into the specific cellular …

Gene-based therapeutics hold great promise for medical advancement and have been used
to treat various human diseases with mixed success. However, their therapeutic application …

Small interfering RNA (siRNA) is a relatively novel nucleic acid-based therapy to treat
diseases such as cancer. Nevertheless, substantial obstacles to its clinical applications have …