Recent advances of α-glucosidase inhibitors: a comprehensive review

N Agrawal, M Sharma, S Singh… - Current topics in …, 2022‏ - benthamdirect.com
Background: Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …

Nutritional and medicinal plants as potential sources of enzyme inhibitors toward the bioactive functional foods: an updated review

H Saleem, A Yaqub, R Rafique… - Critical Reviews in …, 2024‏ - Taylor & Francis
Enzymes are biologically active complex protein molecules that catalyze most chemical
reactions in living organisms, and their inhibitors accelerate biological processes. This …

Alpha-Amylase and Alpha-Glucosidase Enzyme Inhibition and Antioxidant Potential of 3-Oxolupenal and Katononic Acid Isolated from Nuxia oppositifolia

AS Alqahtani, S Hidayathulla, MT Rehman… - Biomolecules, 2019‏ - mdpi.com
Nuxia oppositifolia is traditionally used in diabetes treatment in many Arabian countries;
however, scientific evidence is lacking. Hence, the present study explored the antidiabetic …

Antidiabetic properties of dietary phenolic compounds: Inhibition effects on α‐amylase, aldose reductase, and α‐glycosidase

Y Demir, L Durmaz, P Taslimi… - … and applied biochemistry, 2019‏ - Wiley Online Library
Abstract Aldose reductase (AR), α‐amylase, and α‐glycosidase are vital enzymes to prevent
diabetic complications. Here, AR was purified from sheep kidney using elementary methods …

In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir

RT Feunaing, AN Tamfu, AJY Gbaweng… - Molecules, 2022‏ - mdpi.com
Diabetes mellitus is a metabolic disorder which is one of the leading causes of mortality and
morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb …

[HTML][HTML] Extraction of bioactive compounds for antioxidant, antimicrobial, and antidiabetic applications

FS Aldughaylibi, MA Raza, S Naeem, H Rafi, MW Alam… - Molecules, 2022‏ - mdpi.com
This study was designed to check the potential of secondary metabolites of the selected
plants; Citrullus colocynthis, Solanum nigrum, Solanum surattense, Calotropis procera …

[HTML][HTML] α-glucosidase inhibitory, antioxidant activity, and GC/MS analysis of Descurainia sophia methanolic extract: In vitro, in vivo, and in silico studies

M Sadeghi, MS Khomartash… - Arabian journal of …, 2022‏ - Elsevier
Due to the presence of various phenolic compounds in D. sophia, this plant may have an
inhibitory effect on α-Glc and ultimately diabetes control. Therefore, this work aims to …

Chemical profile, antioxidant, antimicrobial, enzyme inhibitory, and cytotoxicity of seven Apiaceae species from Turkey: A comparative study

G Zengin, KI Sinan, G Ak, MF Mahomoodally… - Industrial crops and …, 2020‏ - Elsevier
Several Apiaceae species, used as both food and in complementary and alternative
medicine, represents a rich source of potential valuable phytopharmaceuticals which …

Antidiabetic activity of watermelon (Citrullus lanatus) juice in alloxan-induced diabetic rats

BO Ajiboye, MT Shonibare, BE Oyinloye - Journal of Diabetes & Metabolic …, 2020‏ - Springer
Introduction Watermelon is one of the commonly eaten fruit in most homes in Nigeria and
has been used in the management of diabetes mellitus traditionally. This study was carried …

Phytochemical analysis and biological evaluation of Ferulago setifolia K. Koch

S Gözcü, Z Akşit, S Şimşek, A Kandemir… - Journal of the …, 2024‏ - Wiley Online Library
Abstract BACKGROUND Ferulago setifolia K. Koch (Apiaceae) has been the subject of this
study, aiming to comprehensively determine its phenolic fingerprint and evaluate its various …