The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …

Hyaluronic acid (HA) is a natural polysaccharide with good biocompatibility and
degradability. HA and its derivatives can be used as sustained-release carriers for drugs …

Polysaccharides or polymeric carbohydrate molecules are long chains of monosaccharides
that are linked by glycosidic bonds. The naturally based structural materials are widely …

Polysaccharides are natural biological molecules that have numerous advantages for
theranostics, the integrated approach of therapeutics and diagnostics. Their derivable …

In recent years, tremendous advancements in nanomedicine have resulted in the rapid
development of various nanoformulations, especially the treatment of solid tumors. Despite …

Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

Therapeutic gene silencing promises significant progress in pharmacotherapy, including
considerable expansion of the druggable target space and the possibility for treating orphan …

Hyaluronic acid (HA) is a biodegradable, biocompatible, nontoxic, and non-immunogenic
glycosaminoglycan used for various biomedical applications. The interaction of HA with the …

The cell-surface glycoprotein CD44 is involved in a multitude of important physiological
functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte …