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Transgenic fluorescent zebrafish lines that have revolutionized biomedical research
CP Choe, SY Choi, Y Kee, MJ Kim, SH Kim… - Laboratory Animal …, 2021 - Springer
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …
vertebrate model organism in more than 40,000 biomedical research studies. Especially …
Molecular genetics of axis formation in zebrafish
AF Schier, WS Talbot - Annu. Rev. Genet., 2005 - annualreviews.org
The basic vertebrate body plan of the zebrafish embryo is established in the first 10 hours of
development. This period is characterized by the formation of the anterior-posterior and …
development. This period is characterized by the formation of the anterior-posterior and …
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
PB Yu, CC Hong, C Sachidanandan, JL Babitt… - Nature chemical …, 2008 - nature.com
Bone morphogenetic protein (BMP) signals coordinate developmental patterning and have
essential physiological roles in mature organisms. Here we describe the first known small …
essential physiological roles in mature organisms. Here we describe the first known small …
Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein
Angiogenesis, the formation of new blood vessels from pre-existing vessels, is critical to
most physiological processes and many pathological conditions. During zebrafish …
most physiological processes and many pathological conditions. During zebrafish …
Self-formation of layered neural structures in three-dimensional culture of ES cells
M Eiraku, Y Sasai - Current opinion in neurobiology, 2012 - Elsevier
In vitro neural differentiation culture of embryonic stem cells (ESCs) provides a promising
tool for preparing neural cells for replacement therapies and a versatile system for …
tool for preparing neural cells for replacement therapies and a versatile system for …
[HTML][HTML] The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis
JA Tucker, KA Mintzer, MC Mullins - Developmental cell, 2008 - cell.com
Patterning of the vertebrate anteroposterior (AP) axis proceeds temporally from anterior to
posterior. How dorsoventral (DV) axial patterning relates to AP temporal patterning is …
posterior. How dorsoventral (DV) axial patterning relates to AP temporal patterning is …
Bmp and Fgf signaling are essential for liver specification in zebrafish
Based on data from in vitro tissue explant and ex vivo cell/bead implantation experiments,
Bmp and Fgf signaling have been proposed to regulate hepatic specification. However …
Bmp and Fgf signaling have been proposed to regulate hepatic specification. However …
[HTML][HTML] Pleiotropic functions of embryonic sonic hedgehog expression link jaw and taste bud amplification with eye loss during cavefish evolution
Y Yamamoto, MS Byerly, WR Jackman… - Developmental biology, 2009 - Elsevier
This study addresses the role of sonic hedgehog (shh) in increasing oral–pharyngeal
constructive traits (jaws and taste buds) at the expense of eyes in the blind cavefish …
constructive traits (jaws and taste buds) at the expense of eyes in the blind cavefish …
Mesoderm induction: from caps to chips
D Kimelman - Nature Reviews Genetics, 2006 - nature.com
Vertebrate mesoderm induction is one of the classical problems in developmental biology.
Various developmental biology approaches, particularly in Xenopus and zebrafish, have …
Various developmental biology approaches, particularly in Xenopus and zebrafish, have …
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway
C Lengerke, S Schmitt, TV Bowman, IH Jang… - Cell stem cell, 2008 - cell.com
The formation of blood in the embryo is dependent on bone morphogenetic protein (BMP),
but how BMP signaling intersects with other regulators of hematopoietic development is …
but how BMP signaling intersects with other regulators of hematopoietic development is …