G protein-coupled receptors (GPCRs) are important drug targets that mediate various
signaling pathways by activating G proteins and engaging β-arrestin proteins. Despite its …

Apelin receptor (APJ), a member of the class A family of G protein-coupled receptor (GPCR),
plays a crucial role in regulating cardiovascular and central nervous systems function. APJ …

G protein-coupled receptors (GPCRs) represent promising therapeutic targets due to their
involvement in numerous physiological processes mediated by downstream G protein-and β …

Liquid–liquid phase separation has been recognized as universal mechanisms in living
cells for the formation of RNA-protein condensates and ordered lipid domains. These …

Abstract Dopamine D2 receptor (D2R), a G‐protein‐coupled receptor (GPCR), plays critical
roles in neural functions and represents the target for a wide variety of drugs used to treat …

Fluorescent ligands for G-protein coupled receptors (GPCRs) are valuable tools for studying
the expression, pharmacology and modulation of these therapeutically important proteins in …

Eukaryotic cells transmit extracellular signal information to cellular interiors through the
formation of a ternary complex made up of a ligand (or agonist), G-protein, and G-protein …

Single-molecule imaging provides information on diffusion dynamics, oligomerization, and
protein-protein interactions in living cells. To simultaneously monitor different types of …

抄録 The G–protein coupled receptor (GPCR) belongs to one of the most renowned protein
super families. Over the past couple of decades, researchers have studied the dynamic …

Single‐molecule live‐cell imaging is the most direct approach for monitoring the motility of
molecules in living cells. Considering the relationship between the motility of molecules and …