Antiviral approaches against influenza virus

R Kumari, SD Sharma, A Kumar, Z Ende… - Clinical microbiology …, 2023 - journals.asm.org
Preventing and controlling influenza virus infection remains a global public health
challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are …

Bat-borne virus diversity, spillover and emergence

M Letko, SN Seifert, KJ Olival, RK Plowright… - Nature Reviews …, 2020 - nature.com
Most viral pathogens in humans have animal origins and arose through cross-species
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus …

Influenza A virus cell entry, replication, virion assembly and movement

D Dou, R Revol, H Östbye, H Wang… - Frontiers in …, 2018 - frontiersin.org
Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait
provides influenza with the advantage of access to the nuclear machinery during replication …

Influenza virus neuraminidase structure and functions

JL McAuley, BP Gilbertson, S Trifkovic… - Frontiers in …, 2019 - frontiersin.org
With the constant threat of emergence of a novel influenza virus pandemic, there must be
continued evaluation of the molecular mechanisms that contribute to virulence. Although the …

[HTML][HTML] The evolution of seasonal influenza viruses

VN Petrova, CA Russell - Nature Reviews Microbiology, 2018 - nature.com
Despite decades of surveillance and pharmaceutical and non-pharmaceutical interventions,
seasonal influenza viruses continue to cause epidemics around the world each year. The …

H19 influenza A virus exhibits species-specific MHC class II receptor usage

U Karakus, I Mena, J Kottur, SS El Zahed, R Seoane… - Cell host & …, 2024 - cell.com
Avian influenza A virus (IAV) surveillance in Northern California, USA, revealed unique IAV
hemagglutinin (HA) genome sequences in cloacal swabs from lesser scaups. We found two …

Next-generation influenza vaccines: opportunities and challenges

CJ Wei, MC Crank, J Shiver, BS Graham… - Nature reviews Drug …, 2020 - nature.com
Seasonal influenza vaccines lack efficacy against drifted or pandemic influenza strains.
Develo** improved vaccines that elicit broader immunity remains a public health priority …

Genetic characterization of a new candidate hemagglutinin subtype of influenza A viruses

S Fereidouni, E Starick, K Karamendin… - Emerging microbes & …, 2023 - Taylor & Francis
Avian influenza viruses (AIV) have been classified on the basis of 16 subtypes of
hemagglutinin (HA) and 9 subtypes of neuraminidase. Here we describe genomic evidence …

Nutritional aspects and health benefits of bioactive plant compounds against infectious diseases: a review

MT El-Saadony, NM Zabermawi… - Food Reviews …, 2023 - Taylor & Francis
In the current century, the development of medicine and molecular biotechnology led to
successful containment and even eradication of some human pathogens, especially in …

Drug resistance in influenza A virus: the epidemiology and management

M Hussain, HD Galvin, TY Haw… - Infection and drug …, 2017 - Taylor & Francis
Influenza A virus (IAV) is the sole cause of the unpredictable influenza pandemics and
deadly zoonotic outbreaks and constitutes at least half of the cause of regular annual …