Pathogenesis of West Nile Virus infection: a balance between virulence, innate and adaptive immunity, and viral evasion
West Nile virus (WNV) is a neurotropic ffavivirus that has emerged globally as a significant
cause of viral encephalitis. WNV is maintained in an enzootic cycle between mosquitoes …
cause of viral encephalitis. WNV is maintained in an enzootic cycle between mosquitoes …
Domain III peptides from flavivirus envelope protein are useful antigens for serologic diagnosis and targets for immunization
The Flavivirus genus of the Flaviviridae family includes 70 enveloped single-stranded-RNA
positive-sense viruses transmitted by arthropods. Among these viruses, there are a relevant …
positive-sense viruses transmitted by arthropods. Among these viruses, there are a relevant …
Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus
T Oliphant, M Engle, GE Nybakken, C Doane… - Nature medicine, 2005 - nature.com
Abstract Neutralization of West Nile virus (WNV) in vivo correlates with the development of
an antibody response against the viral envelope (E) protein. Using random mutagenesis …
an antibody response against the viral envelope (E) protein. Using random mutagenesis …
Type-and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes
S Sukupolvi-Petty, SK Austin, WE Purtha… - Journal of …, 2007 - Am Soc Microbiol
Neutralization of flaviviruses in vivo correlates with the development of an antibody
response against the viral envelope (E) protein. Previous studies demonstrated that …
response against the viral envelope (E) protein. Previous studies demonstrated that …
The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1
B Shrestha, JD Brien, S Sukupolvi-Petty… - PLoS …, 2010 - journals.plos.org
Antibody protection against flaviviruses is associated with the development of neutralizing
antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) …
antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) …
Infectious cDNA clone of the epidemic West Nile virus from New York City
PY Shi, M Tilgner, MK Lo, KA Kent… - Journal of virology, 2002 - Am Soc Microbiol
We report the first full-length infectious clone of the current epidemic, lineage I, strain of West
Nile virus (WNV). The full-length cDNA was constructed from reverse transcription-PCR …
Nile virus (WNV). The full-length cDNA was constructed from reverse transcription-PCR …
Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein
The flavivirus envelope protein is the dominant antigen in eliciting neutralizing antibodies
and plays an important role in inducing immunologic responses in the infected host. We …
and plays an important role in inducing immunologic responses in the infected host. We …
A functional epitope determinant on domain III of the Japanese encephalitis virus envelope protein interacted with neutralizing-antibody combining sites
The envelope (E) protein of Japanese encephalitis virus (JEV) is associated with viral
binding to cellular receptors, membrane fusion, and the induction of protective neutralizing …
binding to cellular receptors, membrane fusion, and the induction of protective neutralizing …
Screening of protective antigens of Japanese encephalitis virus by DNA immunization: a comparative study with conventional viral vaccines
In this study, we evaluated the relative role of the structural and nonstructural proteins of the
Japanese encephalitis virus (JEV) in inducing protective immunities and compared the …
Japanese encephalitis virus (JEV) in inducing protective immunities and compared the …
Structural and molecular analyses of functional epitopes and escape mutants in Japanese encephalitis virus envelope protein domain III
U Roy - Immunologic Research, 2020 - Springer
The Japanese encephalitis virus (JEV) is one of the vector borne causes of encephalitis
found in southeastern Asia. This positive single-stranded RNA virus is a member of the …
found in southeastern Asia. This positive single-stranded RNA virus is a member of the …