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Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …
the development of mesoporous materials, their different synthetic routes and their use as …
[Retracted] U‐Net‐Based Medical Image Segmentation
Deep learning has been extensively applied to segmentation in medical imaging. U‐Net
proposed in 2015 shows the advantages of accurate segmentation of small targets and its …
proposed in 2015 shows the advantages of accurate segmentation of small targets and its …
Nanomedicine tumor targeting
T Lammers - Advanced Materials, 2024 - Wiley Online Library
Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …
Smart cancer nanomedicine
Nanomedicines are extensively employed in cancer therapy. We here propose four strategic
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …
Polymersome-based protein drug delivery–quo vadis?
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …
approaches and represent one of the fastest growing families of drugs. While many of these …
Quantifying the ligand-coated nanoparticle delivery to cancer cells in solid tumors
Coating the nanoparticle surface with cancer cell recognizing ligands is expected to facilitate
specific delivery of nanoparticles to diseased cells in vivo. While this targeting strategy is …
specific delivery of nanoparticles to diseased cells in vivo. While this targeting strategy is …
Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study
Biocompatible gold nanoparticles designed to absorb light at wavelengths of high tissue
transparency have been of particular interest for biomedical applications. The ability of such …
transparency have been of particular interest for biomedical applications. The ability of such …
Mechanisms and barriers in nanomedicine: progress in the field and future directions
In recent years, steady progress has been made in synthesizing and characterizing
engineered nanoparticles, resulting in several approved drugs and multiple promising …
engineered nanoparticles, resulting in several approved drugs and multiple promising …
Alliance with EPR effect: combined strategies to improve the EPR effect in the tumor microenvironment
The use of nanomedicine for cancer treatment takes advantage of its preferential
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …
Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …