Small nucleolar RNAs (snoRNAs), a type of non-coding RNA, are widely present in the
nucleoli of eukaryotic cells and play an important role in rRNA modification. With the recent …

Small nucleolar RNAs (SnoRNAs) are a class of non-coding RNAs divided into two classes:
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …

The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

The biosynthesis of ribosomes is a complex process that requires the coordinated action of
many factors and a huge energy investment from the cell. Ribosomes are essential for …

Ribosomes are nanomachines essential for protein production in all living cells. Ribosome
synthesis increases in cancer cells to cope with a rise in protein synthesis and sustain …

Cellular senescence is a tumour suppressor programme characterized by a stable cell cycle
arrest. Here we report that cellular senescence triggered by a variety of stimuli leads to …

Ribosomes are perhaps the most critical macromolecular machine as they are tasked with
carrying out protein synthesis in cells. They are incredibly complex structures composed of …

Methylcytosine (m5C) is a base modification broadly found on various RNAs in the human
transcriptome. In eukaryotes, m5C is catalyzed by enzymes of the NSUN family composed of …

NAT10 is an essential enzyme that catalyzes N 4-acetylcytidine (ac4C) in eukaryotic transfer
RNA and 18S ribosomal RNA. Recent studies suggested that rRNA acetylation is dependent …

Small nucleolar RNAs (snoRNAs) play critical roles in various biological processes. The
aberrant expression or depletion of snoRNAs is related to various diseases. In previous …