Cartilage defects in the knee are being diagnosed with increased frequency and are treated
with a variety of techniques. The aim of any cartilage repair procedure is to generate the …

Biomaterials play a core role in cartilage repair and regeneration. The success or failure of
an implanted biomaterial is largely dependent on host response following implantation. Host …

Articular cartilage repair has been a long-standing challenge in orthopaedic medicine due to
the limited self-regenerative capability of cartilage tissue. Currently, cartilage lesions are …

MSCs are known as multipotent mesenchymal stem cells that have been found capable of
differentiating into various lineages including cartilage. However, recent studies suggest …

Bioprinting is a promising tool to fabricate organized cartilage. This study aimed to
investigate the printability of gelatin-methacryloyl/gellan gum (gelMA/gellan) hydrogels with …

Background: Chondral and osteochondral lesions are being detected with increasing
frequency. For large-diameter lesions, cell-based treatment modalities are speculated to …

Regenerative medicine, using cells as therapeutic agents for the repair or regeneration of
tissues and organs, offers great hope for the future of medicine. Cell therapy for treating …

Articular cartilage damaged through trauma or disease has a limited ability to repair.
Untreated, focal lesions progress to generalized changes including osteoarthritis …

Background: The evidence supporting best practice guidelines in the field of cartilage repair
of the ankle are based on both low quality and low levels of evidence. Therefore, an …

Osteoarthritis (OA) is a multifactorial disease leading to degeneration of articular cartilage,
causing morbidity in approximately 8.5 million of the UK population. As the dense …