High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations
Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …
academic, industrial, and clinical research settings. The rise in utilization of mass …
Identification of splice variants and isoforms in transcriptomics and proteomics
Alternative splicing is pivotal to the regulation of gene expression and protein diversity in
eukaryotic cells. The detection of alternative splicing events requires specific omics …
eukaryotic cells. The detection of alternative splicing events requires specific omics …
Applications of tandem mass spectrometry (MS/MS) in protein analysis for biomedical research
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …
[HTML][HTML] Considerations for constructing a protein sequence database for metaproteomics
Mass spectrometry-based metaproteomics has emerged as a prominent technique for
interrogating the functions of specific organisms in microbial communities, in addition to total …
interrogating the functions of specific organisms in microbial communities, in addition to total …
Optimizing single cell proteomics using trapped ion mobility spectrometry for label-free experiments
Although single cell RNA-seq has had a tremendous impact on biological research, a
corresponding technology for unbiased mass spectrometric analysis of single cells has only …
corresponding technology for unbiased mass spectrometric analysis of single cells has only …
Proteomics of the Heart
Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
[PDF][PDF] Necroptosis is associated with Rab27‐independent expulsion of extracellular vesicles containing RIPK3 and MLKL
K Gupta, KA Brown, ML Hsieh… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicle (EV) secretion is an important mechanism used by cells to release
biomolecules. A common necroptosis effector—mixed lineage kinase domain like (MLKL) …
biomolecules. A common necroptosis effector—mixed lineage kinase domain like (MLKL) …
An overview of technologies for MS-based proteomics-centric multi-omics
Introduction Mass spectrometry-based proteomics reveals dynamic molecular signatures
underlying phenotypes reflecting normal and perturbed conditions in living systems …
underlying phenotypes reflecting normal and perturbed conditions in living systems …
One-pot exosome proteomics enabled by a photocleavable surfactant
Exosomes are small extracellular vesicles (EVs) secreted by all cells and found in biological
fluids, which can serve as minimally invasive liquid biopsies with extremely high therapeutic …
fluids, which can serve as minimally invasive liquid biopsies with extremely high therapeutic …
Digital Microfluidics for Microproteomic Analysis of Minute Mammalian Tissue Samples Enabled by a Photocleavable Surfactant
Proteome profiles of precious tissue samples have great clinical potential for accelerating
disease biomarker discovery and promoting novel strategies for early diagnosis and …
disease biomarker discovery and promoting novel strategies for early diagnosis and …