Functional annotation of proteins is a fundamental problem in the post‐genomic era. The
recent availability of protein interaction networks for many model species has spurred on the …

The elucidation of mechanisms of chromatin remodeling, particular transcriptional activation,
and repression by histone acetylation and deacetylation has shed light on the role of histone …

Deciphering the genetic basis of human diseases is an important goal of biomedical
research. On the basis of the assumption that phenotypically similar diseases are caused by …

A proteome‐wide map** of interactions between hepatitis C virus (HCV) and human
proteins was performed to provide a comprehensive view of the cellular infection. A total of …

Proteins targeting the same subcellular localization tend to participate in mutual protein–
protein interactions (PPIs) and are often functionally associated. Here, we investigated the …

Genome-wide association studies (GWAS) are a valuable approach to understanding the
genetic basis of complex traits. One of the challenges of GWAS is the translation of genetic …

Millions of genetic variants have been assessed for their effects on the trait of interest in
genome-wide association studies (GWAS). The complex traits are affected by a set of inter …

One of the challenging problems in the etiology of diseases is to explore the relationships
between initiation and progression of diseases and abnormalities in local regions of …

The molecular events underlying many human hereditary disorders remain to be discovered
despite the significant advances made in molecular biology and genetics in the past years …

Hub proteins have central roles in regulating cellular processes. By targeting a single
cellular hub, a viral oncogene may gain control over an entire module in the cellular …