[HTML][HTML] Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms
M Kundakovic, D Rocks - Frontiers in neuroendocrinology, 2022 - Elsevier
Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …
underlying biological factors and mechanisms are largely unknown. In this review, we …
Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories
T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …
[HTML][HTML] Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning
The amygdala is a brain region primarily associated with emotional response. The use of
genetic markers and single-cell transcriptomics can provide insights into behavior …
genetic markers and single-cell transcriptomics can provide insights into behavior …
The role of adult hippocampal neurogenesis in brain health and disease
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …
Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by
environmental influences, and functionally implicated in behavioural responses to stress …
environmental influences, and functionally implicated in behavioural responses to stress …
Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …
[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
Encouraging an excitable brain state: mechanisms of brain repair in stroke
MT Joy, ST Carmichael - Nature Reviews Neuroscience, 2021 - nature.com
Stroke induces a plastic state in the brain. This period of enhanced plasticity leads to the
sprouting of new axons, the formation of new synapses and the remap** of sensory-motor …
sprouting of new axons, the formation of new synapses and the remap** of sensory-motor …
Integration of optogenetics with complementary methodologies in systems neuroscience
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …
[HTML][HTML] Anxiety cells in a hippocampal-hypothalamic circuit
The hippocampus is traditionally thought to transmit contextual information to limbic
structures where it acquires valence. Using freely moving calcium imaging and …
structures where it acquires valence. Using freely moving calcium imaging and …