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[HTML][HTML] EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions
One of the malignant tumors in women that has involved both developed and develo**
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …
The roles of m6A methylation in cervical cancer: functions, molecular mechanisms, and clinical applications
Z Mao, B Wang, T Zhang, B Cui - Cell death & disease, 2023 - nature.com
Cervical cancer (CC) is a gynecological neoplasm with the highest incidence rate, primarily
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …
[HTML][HTML] Osteopontin in cancer: mechanisms and therapeutic targets
Despite significant advances in the understanding of cancer biology, cancer is still a leading
cause of death worldwide. Expression of the tumor microenvironment component …
cause of death worldwide. Expression of the tumor microenvironment component …
TTN mutations predict a poor prognosis in patients with thyroid cancer
X Han, J Chen, J Wang, J Xu, Y Liu - Bioscience reports, 2022 - portlandpress.com
Objective: We aimed to investigate the relationship between titin (TTN) gene mutations and
thyroid cancer (THCA) and to explore the feasibility of the TTN gene as a potential …
thyroid cancer (THCA) and to explore the feasibility of the TTN gene as a potential …
YBX1 promotes type H vessel–dependent bone formation in an m5C-dependent manner
YJ Li, Q Guo, MS Ye, GP Cai, WF **ao, S Deng… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
RNA-binding proteins (RBPs) interact with RNA and ubiquitously regulate RNA transcripts
during their life cycle, playing a fundamental role in the progression of angiogenesis-related …
during their life cycle, playing a fundamental role in the progression of angiogenesis-related …
Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer
Background Bone morphogenetic proteins (BMPs) play crucial roles in the tumorigenesis
and metastasis of cancers. Controversy remains about the exact implications of BMPs and …
and metastasis of cancers. Controversy remains about the exact implications of BMPs and …
Osteopontin: A Key Multifaceted Regulator in Tumor Progression and Immunomodulation
The tumor microenvironment (TME) is composed of various cellular components such as
tumor cells, stromal cells including fibroblasts, adipocytes, mast cells, lymphatic vascular …
tumor cells, stromal cells including fibroblasts, adipocytes, mast cells, lymphatic vascular …
Role of osteopontin in cancer development and treatment
Z Yan, X Hu, B Tang, F Deng - Heliyon, 2023 - cell.com
Osteopontin (OPN) is a multifunctional protein secreted intracellularly and extracellularly by
various cell types, including NK cells, macrophages, osteoblasts, T cells, and cancer cells …
various cell types, including NK cells, macrophages, osteoblasts, T cells, and cancer cells …
Passing the post: roles of posttranslational modifications in the form and function of extracellular matrix
JC Adams - American Journal of Physiology-Cell …, 2023 - journals.physiology.org
The extracellular matrix (ECM) is central to the physiology of animal tissues, through its
multifaceted roles in tissue structure, mechanical properties, and cell interactions, and by its …
multifaceted roles in tissue structure, mechanical properties, and cell interactions, and by its …
[HTML][HTML] Macrophage heterogeneity in bone metastasis
Previous studies illustrated that macrophage, a type of innate immune cell, plays critical
roles in tumour progression and metastasis. Bone is the most frequent site of metastasis for …
roles in tumour progression and metastasis. Bone is the most frequent site of metastasis for …