Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various
cytokines have been documented to play important regulatory roles in determining cardiac …

Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Cardiovascular disease is the leading cause of morbidity and mortality world-wide. Recently,
the role of inflammation in the progression of diseases has significantly attracted …

The IL-10 cytokine family has nine members, four of which are located in the IL10 cluster on
chromosome 1q32. These cytokines are the immune regulatory cytokine IL-10 itself, and the …

Abstract Interleukin (IL)-10 cytokine family members, including IL-10, IL-19, IL-20, IL-22, IL-
24, IL-26 and the distantly related IL-28A, IL-28B, and IL-29, play critical roles in the …

Oxidative stress and inflammation are each implicated independently in the development
and progression of heart failure. Their interaction, however, is also evident throughout the …

Chemotherapy has several adverse effects to patients, some of which are life-threatening.
We hypothesized that Doxorubicin induced microbiome imbalance and intestinal damage …

The aim of the study was to determine the effects of fucoidan on rat myocardial ischemia–
reperfusion (I/R) model and elucidate the potential mechanisms. Myocardial I/R injury was …

Inflammasomes are high molecular weight protein complexes in the cytosol of immune and
other cells that play a critical role in the innate immune system in response to cellular stress …