Abstract Treatment resistant schizophrenia (TRS) refers to the significant proportion of
schizophrenia patients who continue to have symptoms and poor outcomes despite …

Up to 30% of people with schizophrenia do not respond to two (or more) trials of
dopaminergic antipsychotics. They are said to have treatment-resistant schizophrenia (TRS) …

The American Psychiatric Association Practice Guideline for the Treatment of Patients With
Schizophrenia seeks to reduce these substantial psychosocial and public health …

Negative symptoms of schizophrenia remain a major therapeutic challenge. The progress in
the conceptualization and assessment is not yet fully reflected by treatment research …

" The Practice of Electroconvulsive Therapy, Third Edition, provides a comprehensive yet
practical overview of the safe and effective use of ECT, with recommendations applicable …

Objectives: To provide guidance for the optimal administration of electroconvulsive therapy,
in particular maintaining the high efficacy of electroconvulsive therapy while minimising …

Background: Although clozapine is the most effective medication for treatment refractory
schizophrenia, only 40% of people will meet response criteria. We therefore undertook a …

ECT is the oldest and most effective therapy available for the treatment of severe major
depression. It is highly effective in individuals with treatment resistance and when a rapid …

Electroconvulsive therapy (ECT) was initially used for the treatment of schizophrenia, but
over the years with the advent of antipsychotics, its use in schizophrenia has been limited …

Background Evidence for the management of inadequate clinical response to clozapine in
treatment-resistant schizophrenia is sparse. Accordingly, an international initiative was …