Host specificity in the Giardia duodenalis species complex

SM Caccio, M Lalle, SG Svärd - Infection, Genetics and Evolution, 2018 - Elsevier
Giardia duodenalis is a unicellular flagellated parasite that infects the gastrointestinal tract of
a wide range of mammalian species, including humans. Investigations of protein and DNA …

A brief history of IL-9

R Goswami, MH Kaplan - The Journal of Immunology, 2011 - journals.aai.org
IL-9 was first described in the late 1980s as a member of a growing number of cytokines that
had pleiotropic functions in the immune system. Although many biological functions have …

Intestinal immune responses to commensal and pathogenic protozoa

A Sardinha-Silva, EVC Alves-Ferreira… - Frontiers in …, 2022 - frontiersin.org
The physical barrier of the intestine and associated mucosal immunity maintains a delicate
homeostatic balance between the host and the external environment by regulating immune …

Mast cells: multifaceted immune cells with diverse roles in health and disease

KN Rao, MA Brown - Annals of the New York Academy of …, 2008 - Wiley Online Library
Mast cells were discovered more than 100 years ago and until recently, have been
considered renegades of the host with the sole purpose of perpetuating allergy. The …

Advances in understanding Giardia: determinants and mechanisms of chronic sequelae

LA Bartelt, RB Sartor - F1000prime reports, 2015 - pmc.ncbi.nlm.nih.gov
Giardia lamblia is a flagellated protozoan that is the most common cause of intestinal
parasitic infection in children living in resource-limited settings. The pathogenicity of Giardia …

Giardia spp. and the Gut Microbiota: Dangerous Liaisons

E Fekete, T Allain, A Siddiq, O Sosnowski… - Frontiers in …, 2021 - frontiersin.org
Alteration of the intestinal microbiome by enteropathogens is commonly associated with
gastrointestinal diseases and disorders and has far-reaching consequences for overall …

Giardiasis: characteristics, pathogenesis and new insights about treatment

V Vivancos, I González-Alvarez… - Current topics in …, 2018 - ingentaconnect.com
Giardia intestinalis infection causes enterocytes damage and loss of brush border of the
epithelial cells of the intestine that leads to shortening of microvilli and altered epithelial …

New and emerging roles for mast cells in host defence

W Dawicki, JS Marshall - Current opinion in immunology, 2007 - Elsevier
Mast cells are highly effective sentinel cells, found close to blood vessels and especially
common sites of potential infection, such as the skin, airways and gastrointestinal tract. Mast …

Giardia immunity–an update

K Roxström-Lindquist, D Palm, D Reiner… - Trends in …, 2006 - cell.com
Giardia lamblia is a flagellated protozoan that causes watery diarrhea worldwide but the
mechanisms of pathogenicity and the major host defenses against Giardia infection are not …

Biological characteristics of IL-6 and related intestinal diseases

Y Guo, B Wang, T Wang, L Gao, Z Yang… - … journal of biological …, 2021 - pmc.ncbi.nlm.nih.gov
The intestine serves as an important digestive and the largest immune organ in the body.
Interleukin-6 (IL-6), an important mediator of various pathways, participates in the …