The critical role of lumped parameter models in patient-specific cardiovascular simulations

L Garber, S Khodaei, Z Keshavarz-Motamed - Archives of Computational …, 2022 - Springer
Cardiovascular (CV) disease impacts tens of millions of people annually and carries a
massive global economic burden. Continued advances in medical imaging, hardware and …

Material modeling and recent findings in transcatheter aortic valve implantation simulations

O Mutlu, M Saribay, MM Yavuz, HE Salman… - Computer Methods and …, 2024 - Elsevier
Background and objective Transcatheter aortic valve implantation (TAVI) has significantly
transformed the management of aortic valve (AV) diseases, presenting a minimally invasive …

An ultrasound-exclusive non-invasive computational diagnostic framework for personalized cardiology of aortic valve stenosis

N Bahadormanesh, B Tomka, M Kadem… - Medical Image …, 2023 - Elsevier
Aortic stenosis (AS) is an acute and chronic cardiovascular disease and If left untreated,
50% of these patients will die within two years of develo** symptoms. AS is characterized …

A diagnostic, monitoring, and predictive tool for patients with complex valvular, vascular and ventricular diseases

Z Keshavarz-Motamed - Scientific Reports, 2020 - nature.com
Hemodynamics quantification is critically useful for accurate and early diagnosis, but we still
lack proper diagnostic methods for many cardiovascular diseases. Furthermore, as most …

Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling

L Garber, S Khodaei, N Maftoon… - Scientific Reports, 2023 - nature.com
In recent years, transcatheter aortic valve replacement (TAVR) has become the leading
method for treating aortic stenosis. While the procedure has improved dramatically in the …

[HTML][HTML] Early detection of risk of neo-sinus blood stasis post-transcatheter aortic valve replacement using personalized hemodynamic analysis

S Khodaei, M Abdelkhalek, N Maftoon, A Emadi… - Structural Heart, 2023 - Elsevier
Background Despite the demonstrated benefits of transcatheter aortic valve replacement
(TAVR), subclinical leaflet thrombosis and hypoattenuated leaflet thickening are commonly …

A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement

N Bahadormanesh, B Tomka, M Abdelkhalek… - Scientific Reports, 2023 - nature.com
Given the associated risks with transcatheter aortic valve replacement (TAVR), it is crucial to
determine how the implant will affect the valve dynamics and cardiac function, and if TAVR …

Towards non-invasive computational-mechanics and imaging-based diagnostic framework for personalized cardiology for coarctation

R Sadeghi, S Khodaei, J Ganame… - Scientific Reports, 2020 - nature.com
Coarctation of the aorta (COA) is a congenital narrowing of the proximal descending aorta.
Although accurate and early diagnosis of COA hinges on blood flow quantification, proper …