In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Synthetic nanopores have been used to study individual biomolecules in high throughput,
but their performance as sensors does not match that of biological ion channels. Challenges …

Nanopores bear great potential as sensors for single molecules, which are detected as
resistive pulses in a simple electrical measurement. The investigation of proteins requires …

The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

Biological protein pores and pore-forming peptides can generate a pathway for the flux of
ions and other charged or polar molecules across cellular membranes. In nature, these …

The use of a “size-tunable” polyurethane resistive pulse sensor for quantitative sizing of
nano-and microparticles is presented. A linear relationship, as first suggested by Maxwell …

Since their introduction in 2001, solid-state nanopores have been increasingly exploited for
the detection and characterization of biomolecules ranging from single DNA strands to …

Plasma is a rich mine of various biomarkers including proteins, metabolites and circulating
nucleic acids. The diagnostic and therapeutic potential of these analytes has been quite …

This article reviews state-of-the-art microfluidic biosensors of nucleic acids and proteins for
point-of-care (POC) diagnostics. Microfluidics is capable of analyzing small sample volumes …