Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

Point-of-care testing (POCT) technology is urgently required owing to the prevalence of the
Internet of Things and portable electronics. In light of the attractive properties of low …

The ultimate goal of most biomedical research is to gain greater insight into mechanisms of
human disease or to develop new and improved therapies or diagnostics. Although great …

This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …

The recent cataloging of the genomic aberrations in breast cancer has revealed the diversity
and complexity of the disease at the genetic level. To unravel the functional consequences …

Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

Breast tumors grow in a tissue microenvironment containing extracellular matrix (ECM),
adipocytes, stromal cells, fluids, and blood vessels. This natural yet complex …

Most of the anticancer drug candidates entering preclinical trials fail to be approved for
clinical applications. The following are among the main causes of these failures: studying …

In this work, we report a rapid, facile, portable, disposable and low-cost fluorescence and
visual method for multiplexed monitoring of cancer cells using graphene oxide (GO)-based …