Although cardiac action potential (AP) generation and propagation have traditionally been
attributed exclusively to cardiomyocytes (CM), other cell types in the heart are also capable …

The immune and fibrotic responses have evolved to work in tandem to respond to pathogen
clearance and promote tissue repair. However, excessive immune and fibrotic responses …

The medical burden of stroke extends beyond the brain injury itself and is largely
determined by chronic comorbidities that develop secondarily. We hypothesized that these …

Aims The concept of “atrial cardiomyopathy”(AtCM) had been percolating through the
literature since its first mention in 1972. Since then, publications using the term were …

CRISPR‐Cas13 holds substantial promise for tissue repair through its RNA editing
capabilities and swift catabolism. However, conventional delivery methods fall short in …

Endothelial cells (ECs) not only form passive blood conduits but actively contribute to
nutrient transport and organ homeostasis. The role of ECs in glucose homeostasis is …

Atrial fibrillation (AF) is the most common sustained arrhythmia in humans, yet the molecular
basis of AF remains incompletely understood. To determine the cell type-specific …

Cardiac macrophages represent a functionally diverse population of cells involved in
cardiac homeostasis, repair, and remodeling. With recent advancements in single-cell …

Introduction Proprotein convertase subtilisin/kexin type 9 (PCSK9) is implicated in the
pathogenesis and progression of autoimmune disease. Patients with rheumatoid arthritis …

Atrial fibrosis is one of the main manifestations of atrial cardiomyopathy, an array of
electrical, mechanical and structural alterations associated with atrial fibrillation (AF), stroke …