To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

M Giustiniano, A Basso, V Mercalli… - Chemical Society …, 2017 - pubs.rsc.org
The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

One Reacts as Two: Applications of N-Isocyaniminotriphenylphosphorane in Diversity-Oriented Synthesis

GM Ojeda-Carralero, LG Ceballos, J Coro… - ACS Combinatorial …, 2020 - ACS Publications
N-Isocyaniminotriphenylphosphorane (NIITP) is a functionalized isonitrile that has been
extensively applied in a variety of organic reactions during the last two decades. This …

Silver-Mediated [3 + 2] Cycloaddition of Alkynes and N-Isocyanoiminotriphenylphosphorane: Access to Monosubstituted Pyrazoles

F Yi, W Zhao, Z Wang, X Bi - Organic Letters, 2019 - ACS Publications
A silver-mediated [3+ 2] cycloaddition of “CNN” and “C≡ C” for constructing pyrazoles has
been described. The “CNN” building block used is N-isocyanoiminotriphenylphosphorane …

A Cobalt Mediated Nitrene Transfer aza-Wittig Cascade Reaction To Access 1,3,4-Oxadiazole Scaffolds

DS Verdoorn, P Ranjan, T De Reuver, E Janssen… - Organic …, 2023 - ACS Publications
A cobalt (II) mediated three-component synthesis of 5-substituted-N-sulfonyl-1, 3, 4-
oxadiazol-2 (3 H)-imines using sulfonyl azides, N-isocyaniminotriphenylphosphorane …

Silver-Mediated Direct C–H Cyanation of Terminal Alkynes with N-Isocyanoiminotriphenylphosphorane

H Wang, P Mi, W Zhao, R Kumar, X Bi - Organic Letters, 2017 - ACS Publications
A direct cyanation of terminal alkynes for the synthesis of propionitrile derivatives, with the
aid of silver salt using water additive, has been achieved. The cyano source used is N …

Synthesis, carbonic anhydrase inhibition, anticancer activity, and molecular docking studies of 1, 3, 4-oxadiazole derivatives

BD Vanjare, NG Choi, YS Eom, H Raza, M Hassan… - Molecular Diversity, 2023 - Springer
In this work, we have synthesized various organic compounds possessing 1, 3, 4-oxadiazole
as a core structure and the structure of the newly synthesized target compounds has been …

Preparation of fully substituted 1, 3, 4-oxadiazole derivatives from N-isocyaniminotriphenylphosphorane,(E)-cinnamic acids, chloroacetone and primary amines

A Ramazani, FZ Nasrabadi, Z Karimi… - Bulletin of the Korean …, 2011 - koreascience.kr
The 1: 1 imine intermediate generated by the addition of primary amine to chloroacetone is
trapped by N-isocyaniminotriphenylphosphorane in the presence of (E)-cinnamic acids and …

Reactivity of N-(isocyanoimino) triphenylphosphorane toward group 13 Lewis acids

B Tang, S Ju, W Yan, T Chen, DW Stephan… - Chemical …, 2024 - pubs.rsc.org
The species Ph3PNNC 1 reacts with the group 13 Lewis acids E (C6F5) 3 (E= B or Al), HB
(C6F5) 2, ClAl (C6F5) 2 and ECl3 (E= Ga or In) to give the Lewis acid–base adduct …

Progress in Reactions of N‐Isocyanoiminotriphenylphosphorane

Y Wang, C Zhang - ChemistrySelect, 2020 - Wiley Online Library
N‐isocyanoiminotriphenylphosphorane has been widely applied in diverse organic
synthesis due to the favorable structure of isocyano neighbouring iminophosphorane. In this …

Synthesis of 1,3,4-oxadiazoles from the reaction of N-isocyaniminotriphenylphosphorane (NICITPP) with cyclohexanone, a primary amine and an aromatic carboxylic acid via …

A Ramazani, Y Ahmadi, N Fattahi… - … , Sulfur, and Silicon …, 2016 - Taylor & Francis
The 1: 1 imine intermediate generated by the addition of a primary amine to cyclohexanone
trapped by N-isocyaniminotriphenylphosphorane (NICITPP) in the presence of aromatic …