NMR spectroscopy for metabolomics research
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …
three principal analytical techniques used in metabolomics (the other two being gas …
Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease
Cardiomyocytes (CMs) from human induced pluripotent stem cells (hiPSCs) are functionally
immature, but this is improved by incorporation into engineered tissues or forced contraction …
immature, but this is improved by incorporation into engineered tissues or forced contraction …
Recent advances in the application of metabolomics for food safety control and food quality analyses
S Li, Y Tian, P Jiang, Y Lin, X Liu… - Critical reviews in food …, 2021 - Taylor & Francis
As one of the omics fields, metabolomics has unique advantages in facilitating the
understanding of physiological and pathological activities in biology, physiology, pathology …
understanding of physiological and pathological activities in biology, physiology, pathology …
[HTML][HTML] Recent advances in metabolomics analysis for early drug development
Highlights•Metabolomics has become a widely applied tool in drug development.•
Metabolomics plays a key role for the identification of physiological response markers.• …
Metabolomics plays a key role for the identification of physiological response markers.• …
Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease
Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes
mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from …
mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from …
Nuclear magnetic resonance spectroscopy in clinical metabolomics and personalized medicine: current challenges and perspectives
Personalized medicine is probably the most promising area being developed in modern
medicine. This approach attempts to optimize the therapies and the patient care based on …
medicine. This approach attempts to optimize the therapies and the patient care based on …
[HTML][HTML] Metabolite discovery: Biochemistry's scientific driver
Metabolite identification represents a major challenge, and opportunity, for biochemistry.
The collective characterization and quantification of metabolites in living organisms, with its …
The collective characterization and quantification of metabolites in living organisms, with its …
Studying metabolism by NMR-based metabolomics
S Moco - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
During the past few decades, the direct analysis of metabolic intermediates in biological
samples has greatly improved the understanding of metabolic processes. The most used …
samples has greatly improved the understanding of metabolic processes. The most used …
Dimethyl itaconate induces long-term innate immune responses and confers protection against infection
Itaconate is an immunomodulatory metabolite produced by immune cells under microbial
stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti …
stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti …