Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

D Ni, W Bu, EB Ehlerding, W Cai, J Shi - Chemical Society Reviews, 2017 - pubs.rsc.org
Magnetic resonance imaging (MRI) is a highly valuable non-invasive imaging tool owing to
its exquisite soft tissue contrast, high spatial resolution, lack of ionizing radiation, and wide …

Glymphatic MRI in idiopathic normal pressure hydrocephalus

G Ringstad, SAS Vatnehol, PK Eide - Brain, 2017 - academic.oup.com
The glymphatic system has in previous studies been shown as fundamental to clearance of
waste metabolites from the brain interstitial space, and is proposed to be instrumental in …

Recent advances in porphyrin-based MOFs for cancer therapy and diagnosis therapy

Z Wang, Q Sun, B Liu, Y Kuang, A Gulzar, F He… - Coordination Chemistry …, 2021 - Elsevier
Porphyrins and porphyrin derivatives have attracted significant interest in the fields of
catalysis, biosensing, gas storage, solar cells, and biomedical applications owing to their …

Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes

PK Eide, SAS Vatnehol, KE Emblem, G Ringstad - Scientific reports, 2018 - nature.com
Pre-clinical research in rodents provides evidence that the central nervous system (CNS)
has functional lymphatic vessels. In-vivo observations in humans, however, are not …

Clinical quantitative susceptibility map** (QSM): biometal imaging and its emerging roles in patient care

Y Wang, P Spincemaille, Z Liu, A Dimov… - Journal of magnetic …, 2017 - Wiley Online Library
Quantitative susceptibility map** (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

Magnetic nanomaterials as contrast agents for MRI

S Caspani, R Magalhães, JP Araújo, CT Sousa - Materials, 2020 - mdpi.com
Magnetic Resonance Imaging (MRI) is a powerful, noninvasive and nondestructive
technique, capable of providing three-dimensional (3D) images of living organisms. The use …

Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration

J Davies, P Siebenhandl-Wolff, F Tranquart… - Archives of …, 2022 - Springer
Gadolinium-based contrast agents (GBCAs) have transformed magnetic resonance imaging
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …

Gadolinium deposition and the potential for toxicological sequelae–A literature review of issues surrounding gadolinium‐based contrast agents

KA Layne, PI Dargan, JRH Archer… - British journal of clinical …, 2018 - Wiley Online Library
Every year, approximately 30 million magnetic resonance imaging scans are enhanced with
gadolinium‐based contrast agents (GBCAs) worldwide. Although the development of …

Histology and gadolinium distribution in the rodent brain after the administration of cumulative high doses of linear and macrocyclic gadolinium-based contrast agents

J Lohrke, AL Frisk, T Frenzel, L Schöckel… - Investigative …, 2017 - journals.lww.com
Objectives Retrospective studies in patients with primary brain tumors or other central
nervous system pathologies as well as postmortem studies have suggested that gadolinium …