Importance of glial activation in neuropathic pain
J Mika, M Zychowska, K Popiolek-Barczyk… - European journal of …, 2013 - Elsevier
Glia plays a crucial role in the maintenance of neuronal homeostasis in the central nervous
system. The microglial production of immune factors is believed to play an important role in …
system. The microglial production of immune factors is believed to play an important role in …
The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines
PJ Austin, G Moalem-Taylor - Journal of neuroimmunology, 2010 - Elsevier
In a large proportion of individuals nervous system damage may lead to a debilitating
chronic neuropathic pain. Such pain may now be considered a neuro-immune disorder …
chronic neuropathic pain. Such pain may now be considered a neuro-immune disorder …
Emotional consequences of neuropathic pain: insight from preclinical studies
Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain, including neuropathic pain. While this comorbidity is clinically …
suffering from chronic pain, including neuropathic pain. While this comorbidity is clinically …
Reactive astrocytes: critical players in the development of chronic pain
J Tang, M Bair, G Descalzi - Frontiers in psychiatry, 2021 - frontiersin.org
Chronic pain is associated with long term plasticity of nociceptive pathways in the central
nervous system. Astrocytes can profoundly affect synaptic function and increasing evidence …
nervous system. Astrocytes can profoundly affect synaptic function and increasing evidence …
Role of different brain areas in peripheral nerve injury-induced neuropathic pain
Neuropathic pain has been described as the “most terrible of all tortures which a nerve
wound may inflict” and arises as a consequence of nerve injury either of the peripheral or …
wound may inflict” and arises as a consequence of nerve injury either of the peripheral or …
Neurodynamics: is tension contentious?
R Ellis, G Carta, RJ Andrade… - Journal of Manual & …, 2022 - Taylor & Francis
Tensioning techniqueswere the first neurodynamic techniques used therapeutically in the
management of people with neuropathies. This article aims to provide a balanced evidence …
management of people with neuropathies. This article aims to provide a balanced evidence …
PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma
JA Waschek, SM Baca, S Akerman - The journal of headache and pain, 2018 - Springer
The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary
adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large …
adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large …
Sex‐specific transcriptome of spinal microglia in neuropathic pain due to peripheral nerve injury
Neuropathic pain is a prevalent and debilitating chronic disease that is characterized by
activation in glial cells in various pain‐related regions within the central nervous system …
activation in glial cells in various pain‐related regions within the central nervous system …
Brainstem pain-modulation circuitry and its plasticity in neuropathic pain: insights from human brain imaging investigations
Acute pain serves as a protective mechanism that alerts us to potential tissue damage and
drives a behavioural response that removes us from danger. The neural circuitry critical for …
drives a behavioural response that removes us from danger. The neural circuitry critical for …
Entrapment neuropathies: challenging common beliefs with novel evidence
AB Schmid, L Hailey, B Tampin - journal of orthopaedic & sports physical …, 2018 - jospt.org
Entrapment neuropathies are the most prevalent type of peripheral neuropathy and often a
challenge to diagnose and treat. To a large extent, our current knowledge is based on …
challenge to diagnose and treat. To a large extent, our current knowledge is based on …