The rumen microbiome: balancing food security and environmental impacts

I Mizrahi, RJ Wallace, S Moraïs - Nature Reviews Microbiology, 2021 - nature.com
Ruminants produce edible products and contribute to food security. They house a complex
rumen microbial community that enables the host to digest their plant feed through microbial …

The present and future of whole genome sequencing (WGS) and whole metagenome sequencing (WMS) for surveillance of antimicrobial resistant microorganisms …

EA Oniciuc, E Likotrafiti, A Alvarez-Molina, M Prieto… - Genes, 2018 - mdpi.com
Antimicrobial resistance (AMR) surveillance is a critical step within risk assessment
schemes, as it is the basis for informing global strategies, monitoring the effectiveness of …

Impact of sequencing depth on the characterization of the microbiome and resistome

R Zaheer, N Noyes, R Ortega Polo, SR Cook… - Scientific reports, 2018 - nature.com
Developments in high-throughput next generation sequencing (NGS) technology have
rapidly advanced the understanding of overall microbial ecology as well as occurrence and …

Potential reservoirs of antimicrobial resistance in livestock waste and treated wastewater that can be disseminated to agricultural land

AM Ibekwe, AS Bhattacharjee, D Phan… - Science of The Total …, 2023 - Elsevier
Livestock manure, dairy lagoon effluent, and treated wastewater are known reservoirs of
antibiotic resistance genes (ARGs), antibiotic-resistant bacteria (ARB), and virulence factor …

Whole genome sequencing and metagenomics for outbreak investigation, source attribution and risk assessment of food‐borne microorganisms

EFSA Panel on Biological Hazards (EFSA … - Efsa …, 2019 - Wiley Online Library
This Opinion considers the application of whole genome sequencing (WGS) and
metagenomics for outbreak investigation, source attribution and risk assessment of food …

The rumen microbiome as a reservoir of antimicrobial resistance and pathogenicity genes is directly affected by diet in beef cattle

MD Auffret, RJ Dewhurst, CA Duthie, JA Rooke… - Microbiome, 2017 - Springer
Background The emergence and spread of antimicrobial resistance is the most urgent
current threat to human and animal health. An improved understanding of the abundance of …

The fate of foodborne pathogens in manure treated soil

Z Black, I Balta, L Black, PJ Naughton… - Frontiers in …, 2021 - frontiersin.org
The aim of this review was to provide an update on the complex relationship between
manure application, altered pathogen levels and antibiotic resistance. This is necessary to …

Antibiotics: Pharmacokinetics, toxicity, resistance and multidrug efflux pumps

Ç Yılmaz, G Özcengiz - Biochemical pharmacology, 2017 - Elsevier
The discovery of penicillin followed by streptomycin, tetracycline, cephalosporins and other
natural, semi-synthetic and synthetic antimicrobials completely revolutionized medicine by …

Prevalence of antibiotic resistance genes in soils after continually applied with different manure for 30 years

S Peng, Y Feng, Y Wang, X Guo, H Chu… - Journal of Hazardous …, 2017 - Elsevier
A 30 year field experiment with a wheat-soybean crop** system were performed to
compare the long-term anthropogenic influence on soil ARGs. Compared with chemical …

Overexpression of antibiotic resistance genes in hospital effluents over time

WPM Rowe, C Baker-Austin… - Journal of …, 2017 - academic.oup.com
Objectives: Effluents contain a diverse abundance of antibiotic resistance genes that
augment the resistome of receiving aquatic environments. However, uncertainty remains …