Currently cancer treatment is in large part non-specific with respect to treatment. Medication
is often harsh on patients, whereby they suffer several undesired side effects as a result …

Ferritin, a major iron storage protein, is essential to iron homeostasis and is involved in a
wide range of physiologic and pathologic processes. In clinical medicine, ferritin is …

This guideline provides global, evidence-informed recommendations on the use of
indicators for assessing a population's iron status and application of the use of ferritin …

Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …

Background & Aims With the increasing prevalence of liver disease worldwide, there is an
urgent clinical need for reliable methods to diagnose and stage liver pathology. Liver biopsy …

The prevalence of iron overload cardiomyopathy (IOC) is increasing. The spectrum of
symptoms of IOC is varied. Early in the disease process, patients may be asymptomatic …

Background Reference standard indices of iron deficiency and iron overload are generally
invasive, expensive, and can be unpleasant or occasionally risky. Ferritin is an iron storage …

Iron overload is the histological hallmark of genetic hemochromatosis and transfusional
hemosiderosis but also may occur in chronic hepatopathies. This article provides an …

Background Patients with β thalassemia intermedia can have substantial iron overload,
irrespectively of their transfusion status, secondary to increased intestinal iron absorption …

Sickle cell disease (SCD) is a group of inherited autosomal recessive disorders, including
sickle cell anemia, sickle beta-thalassemia, and other hemoglobinopathies, which are …