Mechanochemical principles of spatial and temporal patterns in cells and tissues

A Bailles, EW Gehrels, T Lecuit - Annual review of cell and …, 2022‏ - annualreviews.org
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

Hierarchical graph learning for protein–protein interaction

Z Gao, C Jiang, J Zhang, X Jiang, L Li, P Zhao… - Nature …, 2023‏ - nature.com
Abstract Protein-Protein Interactions (PPIs) are fundamental means of functions and
signalings in biological systems. The massive growth in demand and cost associated with …

Waves in embryonic development

S Di Talia, M Vergassola - Annual review of biophysics, 2022‏ - annualreviews.org
Embryonic development hinges on effective coordination of molecular events across space
and time. Waves have recently emerged as constituting an ubiquitous mechanism that …

Nonreciprocal pattern formation of conserved fields

F Brauns, MC Marchetti - Physical Review X, 2024‏ - APS
In recent years, nonreciprocally coupled systems have received growing attention. Previous
work has shown that the interplay of nonreciprocal coupling and Goldstone modes can drive …

Symmetry, thermodynamics, and topology in active matter

MJ Bowick, N Fakhri, MC Marchetti, S Ramaswamy - Physical Review X, 2022‏ - APS
The name active matter refers to any collection of entities that individually use free energy to
generate their own motion and forces. Through interactions, active particles spontaneously …

Three-dimensional chiral morphodynamics of chemomechanical active shells

S Yin, B Li, XQ Feng - Proceedings of the National Academy of Sciences, 2022‏ - pnas.org
Morphogenesis of active shells such as cells is a fundamental chemomechanical process
that often exhibits three-dimensional (3D) large deformations and chemical pattern …

Cell cycle control during early embryogenesis

SE Brantley, S Di Talia - Development, 2021‏ - journals.biologists.com
Understanding the mechanisms of embryonic cell cycles is a central goal of developmental
biology, as the regulation of the cell cycle must be closely coordinated with other events …

Control of protein-based pattern formation via guiding cues

T Burkart, MC Wigbers, L Würthner, E Frey - Nature Reviews Physics, 2022‏ - nature.com
Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …

Energy partitioning in the cell cortex

S Chen, DS Seara, A Michaud, S Kim, WM Bement… - Nature Physics, 2024‏ - nature.com
Living systems are driven far from thermodynamic equilibrium through the continuous
consumption of ambient energy. In the cell cortex, this energy is invested in the formation of …

Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila

JA Jackson, M Denk-Lobnig, KA Kitzinger, AC Martin - Current Biology, 2024‏ - cell.com
Actin cortex patterning and dynamics are critical for cell shape changes. These dynamics
undergo transitions during development, often accompanying changes in collective cell …