Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Glioblastoma (WHO grade IV astrocytoma) is the most frequent primary brain tumor in adults,
representing a highly heterogeneous group of neoplasms that are among the most …

Glioblastoma multiform (GBM) is the most common malignant glioma of all the brain tumors
and currently effective treatment options are still lacking. GBM is frequently accompanied …

Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …

Nowadays, due to recent advances in molecular biology, the pathogenesis of glioblastoma
is better understood. For the newly diagnosed, the current standard of care is represented by …

Simple Summary This review describes in a very detailed and exhaustive approach the
literature of these last 20 years on glioblastoma targeted therapies in Phases II-IV of 257 …

The receptor for epidermal growth factor (EGFR) is a prime target for cancer therapy across
a broad variety of tumor types. As it is a tyrosine kinase, small molecule tyrosine kinase …

Background: Glioblastoma multiforme (GBM) is the most common and lethal primary
malignancy of the central nervous system (CNS). Despite the proven benefit of surgical …

Brain tumors are the leading cause of cancer-related death in children. Genomic studies
have provided insights into molecular subgroups and oncogenic drivers of pediatric brain …

Simple Summary Glioblastoma is one of the most dangerous tumors of the central nervous
system, and still cannot be fully overcome. We still mainly rely on standard treatments …