Drug repurposing: progress, challenges and recommendations

S Pushpakom, F Iorio, PA Eyers, KJ Escott… - Nature reviews Drug …, 2019 - nature.com
Given the high attrition rates, substantial costs and slow pace of new drug discovery and
development, repurposing of'old'drugs to treat both common and rare diseases is …

Opportunities and obstacles for deep learning in biology and medicine

T Ching, DS Himmelstein… - Journal of the …, 2018 - royalsocietypublishing.org
Deep learning describes a class of machine learning algorithms that are capable of
combining raw inputs into layers of intermediate features. These algorithms have recently …

Concepts of artificial intelligence for computer-assisted drug discovery

X Yang, Y Wang, R Byrne, G Schneider… - Chemical …, 2019 - ACS Publications
Artificial intelligence (AI), and, in particular, deep learning as a subcategory of AI, provides
opportunities for the discovery and development of innovative drugs. Various machine …

A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions

TN Jarada, JG Rokne, R Alhajj - Journal of cheminformatics, 2020 - Springer
Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …

Machine learning approaches and databases for prediction of drug–target interaction: a survey paper

M Bagherian, E Sabeti, K Wang… - Briefings in …, 2021 - academic.oup.com
The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …

Drug repurposing (DR): an emerging approach in drug discovery

M Rudrapal, SJ Khairnar, AG Jadhav - … , molecular aspects and …, 2020 - books.google.com
Drug repurposing (DR)(also known as drug repositioning) is a process of identifying new
therapeutic use (s) for old/existing/available drugs. It is an effective strategy in discovering or …

Review on machine learning-based bioprocess optimization, monitoring, and control systems

PP Mondal, A Galodha, VK Verma, V Singh… - Bioresource …, 2023 - Elsevier
Abstract Machine Learning is quickly becoming an impending game changer for
transforming big data thrust from the bioprocessing industry into actionable output. However …