IL-6/JAK/STAT3 signaling in breast cancer metastasis: biology and treatment

SG Manore, DL Doheny, GL Wong, HW Lo - Frontiers in oncology, 2022 - frontiersin.org
Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

Carcinogenesis: Failure of resolution of inflammation?

A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Accurate prediction of responses to transarterial chemoembolization for patients with hepatocellular carcinoma by using artificial intelligence in contrast-enhanced …

D Liu, F Liu, X **e, L Su, M Liu, X **e, M Kuang… - European …, 2020 - Springer
Objectives We aimed to establish and validate an artificial intelligence–based radiomics
strategy for predicting personalized responses of hepatocellular carcinoma (HCC) to first …

Jak-stat signaling induced by interleukin-6 family cytokines in hepatocellular carcinoma

J Lokau, V Schoeder, J Haybaeck, C Garbers - Cancers, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. It
can be caused by chronic liver cell injury with resulting sustained inflammation, eg, triggered …

[HTML][HTML] Predicting outcomes of atezolizumab and bevacizumab treatment in patients with hepatocellular carcinoma

JW Han, JW Jang - International Journal of Molecular Sciences, 2023 - mdpi.com
A combination of atezolizumab with bevacizumab (AB) is the first regimen that has shown
superiority compared to sorafenib and is now being used as the systemic treatment of choice …

Hsa-circRNA-G004213 promotes cisplatin sensitivity by regulating miR-513b-5p/PRPF39 in liver cancer

L Qin, Z Zhan, C Wei, X Li… - Molecular medicine …, 2021 - spandidos-publications.com
In recent years, increasing evidence has confirmed that exosomal circular RNAs (circRNAs)
serve a crucial role in the prognostic prediction and diagnosis of liver cancer (LC). The …

Ultrasound-based artificial intelligence in gastroenterology and hepatology

JQ Liu, JY Ren, XL Xu, LY **ong… - World Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Artificial intelligence (AI), especially deep learning, is gaining extensive attention for its
excellent performance in medical image analysis. It can automatically make a quantitative …

[HTML][HTML] Sarcopenia is a negative prognostic factor in patients undergoing transarterial chemoembolization (TACE) for hepatic malignancies

SH Loosen, M Schulze-Hagen, P Bruners, F Tacke… - Cancers, 2019 - mdpi.com
Background and Aims: While transarterial chemoembolization (TACE) represents a standard
of therapy for intermediate-stage hepatocellular carcinoma (HCC) and is also routinely …

[HTML][HTML] Altered profiles of circulating cytokines in chronic liver diseases (NAFLD/HCC): Impact of the PNPLA3I148M risk allele

M Kirchmeyer, A Gaigneaux, FA Servais… - Hepatology …, 2023 - journals.lww.com
Background: Individuals carrying the risk variant p. I148M of patatin-like phospholipase
domain-containing protein 3 (PNPLA3) have a higher susceptibility to fatty liver diseases …

The effect of intravenous lidocaine, ketamine, and lidocaine–ketamine combination in colorectal cancer surgery: a randomized controlled trial

H Ostović, B Šimac, M Pražetina, N Bradić… - Anesthesia & …, 2025 - journals.lww.com
BACKGROUND: Colorectal resections are associated with a pronounced inflammatory
response, severe postoperative pain, and postoperative ileus. The aim of this study was to …