Biogenesis and regulatory roles of circular RNAs
Covalently closed, single-stranded circular RNAs can be produced from viral RNA genomes
as well as from the processing of cellular housekee** noncoding RNAs and precursor …
as well as from the processing of cellular housekee** noncoding RNAs and precursor …
CircRNAs in anticancer drug resistance: recent advances and future potential
T Xu, M Wang, L Jiang, L Ma, L Wan, Q Chen, C Wei… - Molecular cancer, 2020 - Springer
CircRNAs are a novel class of RNA molecules with a unique closed continuous loop
structure. CircRNAs are abundant in eukaryotic cells, have unique stability and tissue …
structure. CircRNAs are abundant in eukaryotic cells, have unique stability and tissue …
Emerging roles of circRNAs in the pathological process of myocardial infarction
ZJ Wen, H **n, YC Wang, HW Liu, YY Gao… - … Therapy-Nucleic Acids, 2021 - cell.com
Myocardial infarction (MI) is defined as cardiomyocyte death in a clinical context consistent
with ischemic insult. MI remains one of the leading causes of morbidity and mortality …
with ischemic insult. MI remains one of the leading causes of morbidity and mortality …
The role and clinical potentials of circular RNAs in prostate cancer
Globally, prostate cancer (PCa) is the second most commonly diagnosed cancer in men
globally. Early diagnosis may help in promoting survival in the affected patients. Circular …
globally. Early diagnosis may help in promoting survival in the affected patients. Circular …
Circular RNAs in the tumour microenvironment
Z Ma, Y Shuai, X Gao, X Wen, J Ji - Molecular Cancer, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) are a new class of endogenous non-coding
RNAs (ncRNAs) widely expressed in eukaryotic cells. Mounting evidence has highlighted …
RNAs (ncRNAs) widely expressed in eukaryotic cells. Mounting evidence has highlighted …
Challenges and opportunities for circRNA identification and delivery
J Dong, Z Zeng, Y Huang, C Chen… - Critical reviews in …, 2023 - Taylor & Francis
Circular RNAs (circRNAs) are evolutionarily conserved noncoding RNAs with tissue-specific
expression patterns, and exert unique cellular functions that have the potential to become …
expression patterns, and exert unique cellular functions that have the potential to become …
circRNA-miRNA-mRNA deregulated network in ischemic heart failure patients
Noncoding RNAs (ncRNAs), which include circular RNAs (circRNAs) and microRNAs
(miRNAs), regulate the development of cardiovascular diseases (CVD). Notably, circRNAs …
(miRNAs), regulate the development of cardiovascular diseases (CVD). Notably, circRNAs …
Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation
Circular RNAs (circRNAs) are an integral component of the host competitive endogenous
RNA (ceRNA) network. These noncoding RNAs are characterized by their unique splicing …
RNA (ceRNA) network. These noncoding RNAs are characterized by their unique splicing …
Advanced technological tools to study multidrug resistance in cancer
L Andrei, S Kasas, IO Garrido, T Stanković… - Drug Resistance …, 2020 - Elsevier
The complexity of cancer biology and its clinical manifestation are driven by genetic,
epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic …
epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic …
The implications of ncRNAs in the development of human diseases
E López-Jiménez, E Andrés-León - Non-coding RNA, 2021 - mdpi.com
The mammalian genome comprehends a small minority of genes that encode for proteins
(barely 2% of the total genome in humans) and an immense majority of genes that are …
(barely 2% of the total genome in humans) and an immense majority of genes that are …