Reversible silencing of neuronal activity is a powerful approach for isolating the roles of
specific neuronal populations in circuit dynamics and behavior. In contrast with neuronal …

Neurological disorders affecting the central nervous system (CNS) are still incompletely
understood. Many of these disorders lack a cure and are seeking more specific and effective …

Optogenetic silencing allows time-resolved functional interrogation of defined neuronal
populations. However, the limitations of inhibitory optogenetic tools impose stringent …

Optogenetics allows manipulations of genetically and spatially defined neuronal populations
with excellent temporal control. However, neurons are coupled with other neurons over …

While there exist many Monte Carlo (MC) programs for solving the radiative transfer
equation (RTE) in biological tissues, we have identified a need for an open-source MC …

Transparent graphene-based neural electrode arrays provide unique opportunities for
simultaneous investigation of electrophysiology, various neural imaging modalities, and …

A Monte Carlo method for photon transport has gained wide popularity in biomedical optics
for studying light behaviour in tissue. Nowadays, typical computation times range from a few …

Significance Quantitative photoacoustic tomography (QPAT) exploits the photoacoustic
effect with the aim of estimating images of clinically relevant quantities related to the tissue's …

Monte Carlo (MC) simulation for light propagation in tissue is the gold standard for studying
the light propagation in biological tissue and has been used for years. Interaction of photons …

Widefield fluorescence microscopy is used to monitor the spiking of populations of neurons
in the brain. Widefield fluorescence can originate from indicator molecules at all depths in …