Mitochondria are essential for a diverse array of biological functions. There is increasing
research focus on develo** efficient tools for mitochondria-targeted detection and …

Oxaliplatin was the third Pt-based anticancer drug to be clinically used worldwide. It exhibits
a broad spectrum of anticancer activity and was the first to be approved for the treatment of …

The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor that
affects cellular phenotypes by modulating phagocytosis and metabolism, promoting cell …

Ferroptosis has emerged as a form of programmed cell death and exhibits remarkable
promise for anticancer therapy. However, it is challenging to discover ferroptosis inducers …

Ferroptosis induced by lipid peroxide (LPO) accumulation is an effective cell death pathway
for cancer therapy. However, how to effectively induce ferroptosis at tumor sites and improve …

G-quadruplexes (G4s) are atypical nucleic acid structures involved in basic human
biological processes and are regulated by small molecules. To date, pyridostatin and its …

Lactate dehydrogenase (LDH) is a key enzyme involved in the process of glycolysis,
assisting cancer cells to take in glucose and generate lactate, as well as to suppress and …

For more accurate diagnosis and effective treatment of cancer, we proposed to develop a
hetero-multinuclear metal complex based on the property of apoferritin (AFt) for targeting …

Platinum complexes are potential antitumor drugs in chemotherapy. Their impact on tumor
treatment could be greatly strengthened by combining with immunotherapy. Increasing …

The development of highly efficient and minimally toxic agents with targeting abilities toward
tumor tissues is an ongoing area of research in the fight against cancer. Different from the …