Plethora of research has shed light on the critical role of synaptic dysfunction in various
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …

Major depressive disorder (MDD) is a common mental disorder that severely disrupts
psychosocial function and decreases the quality of life. Although the pathophysiological …

Genome-wide association studies (GWASs) have identified risk loci for suicide attempt (SA),
but deciphering how they confer risk for SA remains largely unknown. This study aims to …

Protein misfolding and its aggregation, known as amyloid aggregates (Aβ), are some of the
major causes of more than 20 diseases such as Parkinson's disease, Alzheimer's disease …

Objective As neuropsychiatric conditions can increase the risk of age-related
neurodegenerative diseases (NDDs), the impact of CNS-active drugs on the risk of …

Many industrial processes, several natural processes involving non-living matter, and all the
processes occurring within living organisms take place in solution. This means that the …

Although the negative association of tobacco smoking with osteoporosis is well-
documented, little is known regarding the shared genetic basis underlying these conditions …

Depression, or major depressive disorder, poses a significant burden for both individuals
and society, affecting approximately 10.8% of the general population. This psychiatric …

Objective Bipolar disorder is a complex and severe mental illness characterised by manic
and depressive episodes that can be triggered and exacerbated by psychosocial …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
loss of dopaminergic neurons in the substantia nigra. Ferroptosis, an iron-dependent form of …